Protein Alignment KLK6 and CG6592

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_648016.1
• Gene: CG6592 / 38687
• FlyBaseID: FBgn0035669
• Length: 438
• Species: Drosophila melanogaster
• Alignment Length: 227
• Identity: 61/227 - (26%)
• Similarity: 97/227 - (42%)
• Gaps: 27/227 - (11%)

Human    34 PYQAALY---TSGHLLCGGVLIHPLWVLTAAHC--KKPNLQVFLGKHNLRQRESSQEQSSVVRAV 93
            |||..:.   ..|...|||.||....|:|||||  ......||||.:.::   :::|:..|...|
  Fly   135 PYQVGMLLQRPKGLYWCGGSLISDKHVITAAHCVDMAKRALVFLGANEIK---NAKEKGQVRLMV 196

Human    94 ------IHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERD----CSANTTSCHILGWGKTAD 148
                  |:|.::......||.::||......:|.|.|:.|.:.    .|.........|||:.|.
  Fly   197 PSENFQIYPTWNPKRLKDDIAIVRLPHAVSFNERIHPIQLPKRHYEYRSFKNKLAIASGWGRYAT 261

Human   149 G--DFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDH----- 206
            |  ...:.::...:.::....|:..:|.......:|... :..:.:|.||||||||....
  Fly   262 GVHAISNVLRYVQLQIIDGRTCKSNFPLSYRGTNICTSG-RNARSTCNGDSGGPLVLQRRHSKKR 325

Human   207 -LRGLVSWGNIPCGSKEKPGVYTNVCRYTNWI 237
             |.|:.|:|:|....:..|..:|.|..|.:||
  Fly   326 VLVGITSFGSIYGCDRGYPAAFTKVASYLDWI 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	59/225 (26%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	61/227 (27%)