Protein Alignment KLK6 and Jon65Ai

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_648015.1
• Gene: Jon65Ai / 38685
• FlyBaseID: FBgn0035667
• Length: 262
• Species: Drosophila melanogaster
• Alignment Length: 268
• Identity: 79/268 - (29%)
• Similarity: 116/268 - (43%)
• Gaps: 43/268 - (16%)

Human     1 MKKLMV-VLSLIAAAWAEE---------------QNKLVHGGPCDKTSHPYQAALYTS---GHLL 46
            ||.|.| :|.:||:|.|.|               :.::..|.|..:...||...|..|   |...
  Fly     1 MKVLAVLLLGVIASATAFEKPVFWKDVPVGKASIEGRITMGYPAYEGKVPYIVGLGFSKNGGGTW 65

Human    47 CGGVLIHPLWVLTAAHCK--KPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQ-DIM 108
            |||.:|...||:||.||.  ..::.::.|   ...|..:|....|.|:      |...|.. ||.
  Fly    66 CGGSIIGNTWVMTAKHCTDGMESVTIYYG---ALWRLQAQYTHWVGRS------DFIEHGSGDIS 121

Human   109 LLRLARPAKLSELIQPLPLER-DCSANTTS---CHILGWGKTAD-GDFPDTIQCAYIHLVSREEC 168
            |:|... .....|:..:.|.| |...|...   ..:.|||||:| |...:.:.|..:.:.....|
  Fly   122 LIRTPH-VDFWSLVNKVELPRYDDRYNNYQGWWALVSGWGKTSDEGGVSEYLNCVDVQIGENSVC 185

Human   169 EHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLR--GLVSWG-NIPCGSKEKPGVYTNV 230
            |:.| |..:.:::|....: .|.:|.||||||||..|..|  |:||:| :..|.|....|: ..|
  Fly   186 ENYY-GSFSGDLICIPTPE-NKGTCSGDSGGPLVIHDGNRQVGIVSFGSSAGCLSNGPKGM-VRV 247

Human   231 CRYTNWIQ 238
            ..|.:||:
  Fly   248 TSYLDWIR 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	67/227 (30%)
Jon65Ai	NP_648015.1	Tryp_SPc	37..254	CDD:214473	67/229 (29%)