Protein Alignment KLK6 and Jon65Aiii

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_648013.1
• Gene: Jon65Aiii / 38683
• FlyBaseID: FBgn0035665
• Length: 274
• Species: Drosophila melanogaster
• Alignment Length: 272
• Identity: 79/272 - (29%)
• Similarity: 115/272 - (42%)
• Gaps: 42/272 - (15%)

Human     3 KLMVVLSLIAA-------------------AWAEEQNKLVHGGPCDKTSHPYQAAL---YTSGHL 45
            |::||.:|..|                   |....:.::.:|........|||..|   .|||..
  Fly     2 KVLVVFALALATASAGLLPQQVPIHPRDLPAVTNIEGRITNGKTATSGQFPYQVGLSFASTSGSW 66

Human    46 LCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQRESSQ--EQSSVVRAVIHPDYDAASHDQDIM 108
            .|||.:|...||||||||......|.: .:....|.|:|  :..|....|.|..|::.....||.
  Fly    67 WCGGSIIDNTWVLTAAHCTSGASAVTI-YYGATVRTSAQLVQTVSADNFVQHASYNSIVLRNDIS 130

Human   109 LLRLARPAKLSELIQPLPLERDCSANTTSCH------ILGWGKTADG--DFPDTIQCAYIHLVSR 165
            |::....| .:.||.  .:|....|.|.|.:      ..|||||:|.  ...:|:|.....:||.
  Fly   131 LIKTPTVA-FTALIN--KVELPAIAGTYSTYTGQQAIASGWGKTSDSATSVANTLQYEVFEVVSV 192

Human   166 EECEHAYPGQI-TQNMLC-AGDEKYGKDSCQGDSGGP--LVCGDHLRGLVSWGNIPCGSKEKPGV 226
            .:|::.|...: |.|::| |...|.  .:|.||||||  ||....|.|:.|:.:........|..
  Fly   193 SQCQNTYGSLVATNNVICVATPNKV--STCNGDSGGPLVLVSDSKLIGVTSFVSSAGCESGAPAG 255

Human   227 YTNVCRYTNWIQ 238
            :|.|..|.:||:
  Fly   256 FTRVTSYLDWIK 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	71/230 (31%)
Jon65Aiii	NP_648013.1	Tryp_SPc	39..266	CDD:214473	71/232 (31%)