Protein Alignment KLK6 and CG10477

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_648010.1
• Gene: CG10477 / 38679
• FlyBaseID: FBgn0035661
• Length: 272
• Species: Drosophila melanogaster
• Alignment Length: 269
• Identity: 75/269 - (27%)
• Similarity: 118/269 - (43%)
• Gaps: 35/269 - (13%)

Human     1 MKKLMVVLSLIAAAWAE--EQNKLVH----------------GGPCDKTSHPYQAAL---YTSGH 44
            ||...|::..||...|:  .|:..||                |........|||..|   .::|.
  Fly     1 MKVFAVLVLAIATVSADILRQDTPVHPRDSSAVPSIDGRITNGNKAAANQFPYQVGLSFKSSAGS 65

Human    45 LLCGGVLIHPLWVLTAAHCKK--PNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDI 107
            ..|||.:|...||||||||.|  .::.::.|. .:|.....:::.|..:.|.|..|:||:...||
  Fly    66 WWCGGSIIANTWVLTAAHCTKGASSVTIYYGS-TVRTSAKLKKKVSSSKFVQHAGYNAATLRNDI 129

Human   108 MLLRLARPAKLSELIQPLPLERDCSANTT----SCHILGWGKTADGDF--PDTIQCAYIHLVSRE 166
            .|:: ......:..|..:.|....|:.:|    :....|||:|:|...  ...:|.|...:::..
  Fly   130 SLIK-TPSVTFTVSINKIALPAIASSYSTYAGQTAVASGWGRTSDSSIAVATNLQYAQFQVITNA 193

Human   167 ECEHAYPGQ-ITQNMLCAGDEKYGKDS-CQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTN 229
            .|:..:... :|..::|.  |...|.| |||||||||...:.|.|:.|:.:.....|..|..:|.
  Fly   194 VCQKTFGSSVVTSGVICV--ESINKKSTCQGDSGGPLALNNRLIGVTSFVSSKGCEKNAPAGFTR 256

Human   230 VCRYTNWIQ 238
            |..|.:||:
  Fly   257 VTSYLDWIK 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	66/242 (27%)
CG10477	NP_648010.1	Tryp_SPc	39..264	CDD:214473	64/228 (28%)