Protein Alignment KLK6 and CG32277

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_728835.1
• Gene: CG32277 / 38393
• FlyBaseID: FBgn0052277
• Length: 261
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 79/259 - (30%)
• Similarity: 124/259 - (47%)
• Gaps: 24/259 - (9%)

Human     4 LMVVLSLI-----AAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC 63
            |::.|:|:     ::.:...|.|:..|.......|.:...|...|...||||:|.|..|||||||
  Fly     4 LLIGLALLHQLEGSSLFTLRQGKIFGGKTTLVKDHSFLVNLRRGGKFRCGGVIISPNCVLTAAHC 68

Human    64 KKPNLQVF--LGKHNLRQRESSQEQSSVVRAV----IHPDYDA-ASHDQDIMLLRLARPAKLSEL 121
            .:...|..  |..|..:|..........||:.    :.|:|.| ...|.|:.::||:||..::..
  Fly    69 LEGRYQQVRDLTVHAQQQCLGDDMPPEHVRSAWYVGLSPNYCAQRGLDSDLAVIRLSRPFDIAGN 133

Human   122 IQPLPLERDCSANTTSCHILGWGKTAD--GDFPDTIQCAYIHLVSREECEHAYPG---QITQNML 181
            ...:.::.:.....::..:||||...:  .::...:|.|.:.|:|..||..:...   ::|.||.
  Fly   134 ASLVKIDYNDLPPHSNLTVLGWGAINEQGHNWNQCLQEANVKLISHRECIKSVGSGWQKVTNNMF 198

Human   182 CA-GDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVC--RYTNWIQKTIQ 242
            || |  |..:|:||||||||.:......|:|||| ..||| ..|||||.:.  ..|.|::..|:
  Fly   199 CALG--KNARDACQGDSGGPAIYAGRSVGIVSWG-YGCGS-GYPGVYTRLSSPSITYWLKDFIE 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	72/228 (32%)
CG32277	NP_728835.1	Tryp_SPc	27..246	CDD:238113	71/222 (32%)