Protein Alignment KLK6 and CG13430

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_001027441.1
• Gene: CG13430 / 3772580
• FlyBaseID: FBgn0034518
• Length: 267
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 88/267 - (32%)
• Similarity: 127/267 - (47%)
• Gaps: 36/267 - (13%)

Human     3 KLMVVLSLIAAAWA------EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAA 61
            :|.|.|.||..:.|      |:..::|.|.....|..|:|.:|.......|||.:|.|..:||||
  Fly     7 RLAVALWLICTSAAQNSTDVEQDGRIVGGWETHITFFPHQVSLQLGTRHACGGTIISPNIILTAA 71

Human    62 HC----KKPNLQVFLGKHNLRQRESSQEQSS------VVRAVIHPDY-DAASHDQDIMLLRLARP 115
            ||    .||...|.        |..|.:.:.      |.:.:.||:: |....:.||.:::|.:|
  Fly    72 HCVLEYSKPQYYVI--------RAGSSDWTKGGSYIRVKKIIPHPEFHDPTRMNNDIAIVQLQQP 128

Human   116 AKLSELIQPLPL--ERDCSANTTSCHILGWGKTADGDFPDTIQCAY--IHLVSREECEHAY--PG 174
            ...|:.|:|:.|  .:|....|....:.|||.|:........:..|  :||..:.:|...|  .|
  Fly   129 LVYSQDIRPISLATSKDIIMPTAQLFVSGWGSTSISQMQPEKRLRYTVVHLRDQNQCARNYFGAG 193

Human   175 QITQNMLCAGDEKYGKDSCQGDSGGPLVCGD----HLRGLVSWGNIPCGSKEKPGVYTNVCRYTN 235
            .:|..|.|||.:..|:||||||||||||...    .|.|:|||| ..|.:...||:||.|..|.:
  Fly   194 TVTNTMFCAGTQAGGRDSCQGDSGGPLVTSIDGRLKLYGIVSWG-FGCANAMFPGIYTKVSAYDD 257

Human   236 WIQKTIQ 242
            ||.:||:
  Fly   258 WIAQTIE 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	77/234 (33%)
CG13430	NP_001027441.1	Tryp_SPc	31..259	CDD:214473	77/236 (33%)