Protein Alignment KLK6 and CG9897

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_001286753.2
• Gene: CG9897 / 37651
• FlyBaseID: FBgn0034807
• Length: 265
• Species: Drosophila melanogaster
• Alignment Length: 270
• Identity: 69/270 - (25%)
• Similarity: 115/270 - (42%)
• Gaps: 52/270 - (19%)

Human     5 MVVLSLIAAAW-AEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC----K 64
            :::|.::|..| |....::::|...:....|:.|::..:..|.|||.:|...::||||.|    .
  Fly     5 LILLQIVALPWLALGDQRIINGNTVNIKDAPWYASIIVNSKLKCGGAIISKNYILTAAKCVDGYS 69

Human    65 KPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLER 129
            ..::||.||..:.   .:|...:.:.:..:|..|.:...|.::.||:.......::.|:  |:||
  Fly    70 ARSIQVRLGTSSC---GTSGSIAGICKVKVHSQYSSWRFDNNLALLKTCELLNTTDEIK--PIER 129

Human   130 -------DCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREEC------EHAYPGQITQNML 181
                   :..||.|.|    .|::  |:|.|.|....|.....|:|      .|....:|.....
  Fly   130 ADKVPDDNSRANVTGC----GGRS--GNFLDLILDLRISSGIEEKCFQLPVQLHGTQVRILSQKQ 188

Human   182 CAGDEKY-------------------GKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVY 227
            ||.|.|.                   ||.:|..|.|.|||..:.|.|::|    ..|...||.||
  Fly   189 CAADWKVIPFYLLKGISDLTICTKSPGKGACSTDRGSPLVIDNKLVGILS----RAGCSIKPDVY 249

Human   228 TNVCRYTNWI 237
            .|:..:|||:
  Fly   250 ANILGHTNWL 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	64/249 (26%)
CG9897	NP_001286753.2	Tryp_SPc	22..258	CDD:214473	63/250 (25%)