Protein Alignment KLK6 and CG30283

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_611587.2
• Gene: CG30283 / 37454
• FlyBaseID: FBgn0260477
• Length: 273
• Species: Drosophila melanogaster
• Alignment Length: 276
• Identity: 88/276 - (31%)
• Similarity: 130/276 - (47%)
• Gaps: 48/276 - (17%)

Human     3 KLMVVLSLIAAA-----WAEEQNKLVHGGPCDK----------------TSHPYQAALYTSGHLL 46
            |:.||:.|:||:     .:|..:.|.|  ||..                .|.|:.|.:...|...
  Fly     5 KIFVVVVLLAASSVVVLGSESGSFLEH--PCGTVPISQFKILGGHNAPVASAPWMAMVMGEGGFH 67

Human    47 CGGVLIHPLWVLTAAHC-KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLL 110
            |||.||...:|||:||| ....|:|.||   :.:||:..::.:|....:|.||....|  |:.||
  Fly    68 CGGTLITNRFVLTSAHCIANGELKVRLG---VLEREAEAQKFAVDAMFVHTDYYFDQH--DLALL 127

Human   111 RLARPAKLSELIQPL-----PLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEH 170
            |||:....|:.|.|:     ||.::...:.......|||||........:|...:..:.|.||..
  Fly   128 RLAKRVHYSDNISPICLLLDPLVKNIDEHIVKFRTYGWGKTESRSSSRMLQKTSLFNLHRSECAK 192

Human   171 AYP-GQITQNMLCAGDEKYGKDSCQGDSGGPL---VCGDHLR-----GLVSWGNIPCGSKEKPGV 226
            .|| .||.:|.:||  |....::|.|||||||   |..||::     |:.|:|:..|   .|..|
  Fly   193 QYPHQQINRNHICA--ESANANTCNGDSGGPLTAIVTYDHVQMVFQFGVTSFGHADC---SKATV 252

Human   227 YTNVCRYTNWIQKTIQ 242
            :|||..:.:||..|::
  Fly   253 FTNVMTHLDWIVNTVR 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	77/244 (32%)
CG30283	NP_611587.2	Tryp_SPc	42..263	CDD:214473	74/230 (32%)