Protein Alignment KLK6 and CG4927

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_001033953.1
• Gene: CG4927 / 36852
• FlyBaseID: FBgn0034139
• Length: 362
• Species: Drosophila melanogaster
• Alignment Length: 266
• Identity: 75/266 - (28%)
• Similarity: 107/266 - (40%)
• Gaps: 57/266 - (21%)

Human    22 LVHGGPCDKTSHPYQAALYTSGHLL------CGGVLIHPLWVLTAAHCKK--------------- 65
            :|.|........|:.|.|...|...      ||.::|||.:|||||||.:
  Fly   105 IVGGAKAAGREFPFMALLGQRGKNSSQIDWDCGAIIIHPKFVLTAAHCLETSETKEQRLDPNYDG 169

Human    66 PNLQVFLGK--HNLRQRESSQEQSSVVRAVIHPDY----DAASHDQDIMLLRLARPAKLSELIQP 124
            |...|.||:  :|....::..:...|:..|:||.|    |..|...||.::.|...|..||.:.|
  Fly   170 PKYVVRLGELDYNSTTDDAQPQDFRVLNYVVHPAYGEDDDTGSRKNDIAVVELEMEATFSEYVAP 234

Human   125 LPLERDCSANTTSCHILGWGKTADG------------DFPDTIQCAYIHLVSREECEHAYPGQIT 177
            ..|..|...........|||.|::.            |..|..:|:       :..||...   .
  Fly   235 ACLPLDGGNEQLQVAAAGWGATSESGHASSHLLKVSLDRYDVAECS-------QRLEHKID---V 289

Human   178 QNMLCAGDEKYGKDSCQGDSGGPLV-------CGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTN 235
            :..||||......|:|.||||||:.       |...:.|:.|:| :.||.:..|.|||.|..||:
  Fly   290 RTQLCAGSRSTSADTCYGDSGGPVFVQHPIYSCLKQVIGITSYG-LVCGVQGLPSVYTKVHLYTD 353

Human   236 WIQKTI 241
            ||:..:
  Fly   354 WIENIV 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	73/259 (28%)
CG4927	NP_001033953.1	Tryp_SPc	105..358	CDD:238113	75/263 (29%)