Protein Alignment KLK6 and CG8299

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_611066.1
• Gene: CG8299 / 36751
• FlyBaseID: FBgn0034052
• Length: 260
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 80/259 - (30%)
• Similarity: 131/259 - (50%)
• Gaps: 22/259 - (8%)

Human     4 LMVVLSLIAAAW-------AEEQNKLVHGGPCDKTSHPYQAALYTSGHLL---CGGVLIHPLWVL 58
            |.:.|.|:||..       |.....:|.|...|....|||.::....::|   |||.:..|..|:
  Fly     3 LRLGLFLLAALGVVILTDSASISTHIVGGDQADIADFPYQVSVRLETYMLLHICGGSIYAPRVVI 67

Human    59 TAAHCKKPN----LQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLS 119
            |||||.|..    :::..|::::...|  ::...|.:.:.|..|:..::..||.|:....|.:.|
  Fly    68 TAAHCIKGRYASYIRIVAGQNSIADLE--EQGVKVSKLIPHAGYNKKTYVNDIGLIITREPLEYS 130

Human   120 ELIQPLPLERDCSANTTSCHILGWGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQ---ITQN 179
            .|:||:.:..:...:.....:.||||.|:.|  .|..::...:.::.:..|...|..:   :|..
  Fly   131 ALVQPIAVALEAPPSGAQAVVSGWGKRAEDDEALPAMLRAVELQIIEKSTCGAQYLTKDYTVTDE 195

Human   180 MLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243
            |||||..:.|||:|.|||||||.....|.|:|||| :.||.:..|||||:|..:.:||::..:|
  Fly   196 MLCAGYLEGGKDTCNGDSGGPLAVDGVLVGVVSWG-VGCGREGFPGVYTSVNSHIDWIEEQAEA 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	71/225 (32%)
CG8299	NP_611066.1	Tryp_SPc	27..252	CDD:214473	71/227 (31%)