Protein Alignment KLK6 and Ser8

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Alignment Length: 234
• Identity: 78/234 - (33%)
• Similarity: 110/234 - (47%)
• Gaps: 20/234 - (8%)

Human    21 KLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQRESSQE 85
            ::|.|........|:|.:|..||...|||.:|....::|||||......|    .|||.|..|.:
  Fly    34 RIVGGTASSIEDRPWQVSLQRSGSHFCGGSIISNNIIVTAAHCLDTPTTV----SNLRIRAGSNK 94

Human    86 QS------SVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCHILGWG 144
            ::      .|.....|..|::.|...||.::||.........|:.:.:.....|:.::..|.|||
  Fly    95 RTYGGVLVEVAAIKAHEAYNSNSKINDIGVVRLKTKLTFGSTIKAITMASATPAHGSAASISGWG 159

Human   145 KTA-DGDFPDTIQCAYIHLVSREEC---EHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGD 205
            ||: ||....|:......:|.|.:|   .:.|...|...|:||.  ...||:||||||||||.|.
  Fly   160 KTSTDGPSSATLLFVDTRIVGRSQCGSSTYGYGSFIKATMICAA--ATNKDACQGDSGGPLVSGG 222

Human   206 HLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWI---QKTI 241
            .|.|:||||. .|.....||||.|:....:|:   |||:
  Fly   223 QLVGVVSWGR-DCAVANYPGVYANIAELRDWVLQAQKTV 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	74/223 (33%)
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	74/224 (33%)