Protein Alignment KLK6 and iotaTry

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_523695.1
• Gene: iotaTry / 36223
• FlyBaseID: FBgn0015001
• Length: 252
• Species: Drosophila melanogaster
• Alignment Length: 248
• Identity: 71/248 - (28%)
• Similarity: 110/248 - (44%)
• Gaps: 14/248 - (5%)

Human     4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPN- 67
            ::|:|.|..|:..|...:::.|......:.|:|.::..|....||||:.....::||.||....
  Fly    10 VLVLLLLGDASDVEATGRIIGGSDQLIRNAPWQVSIQISARHECGGVIYSKEIIITAGHCLHERS 74

Human    68 ---LQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLER 129
               ::|.:|..|   .........|....:|..:|:.....||.:|||:.|.......:.:.|..
  Fly    75 VTLMKVRVGAQN---HNYGGTLVPVAAYKVHEQFDSRFLHYDIAVLRLSTPLTFGLSTRAINLAS 136

Human   130 DCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQ----ITQNMLCAGDEKYGK 190
            ...:..|:..:.|||.|.:|...|::|.|.:.::.|.||.....|.    :.:..:||...  ..
  Fly   137 TSPSGGTTVTVTGWGHTDNGALSDSLQKAQLQIIDRGECASQKFGYGADFVGEETICAAST--DA 199

Human   191 DSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243
            |:|.||||||||....|.|:|||| ..|.....||||.:|.....||.|...|
  Fly   200 DACTGDSGGPLVASSQLVGIVSWG-YRCADDNYPGVYADVAILRPWIVKAANA 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	62/221 (28%)
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	62/223 (28%)