Protein Alignment KLK6 and gammaTry

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_725034.1
• Gene: gammaTry / 36221
• FlyBaseID: FBgn0010359
• Length: 253
• Species: Drosophila melanogaster
• Alignment Length: 255
• Identity: 79/255 - (30%)
• Similarity: 119/255 - (46%)
• Gaps: 24/255 - (9%)

Human     1 MKKLMVVLSLIAAAWA---------EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLW 56
            |.|.:::||.:|.|..         :...::|.|.....:|.|:|.:|..||...|||.:.....
  Fly     1 MLKFVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNV 65

Human    57 VLTAAHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVI----HPDYDAASHDQDIMLLRLARPAK 117
            ::|||||.:   .|......:|...|......|..:|.    |..|:|.:...||.::::.....
  Fly    66 IVTAAHCLQ---SVSASVLQIRAGSSYWSSGGVTFSVSSFKNHEGYNANTMVNDIAIIKINGALT 127

Human   118 LSELIQPLPLERDCSANTTSCHILGWGKTADG--DFPDTIQCAYIHLVSREEC---EHAYPGQIT 177
            .|..|:.:.|.....||..:..:.|||..:.|  ..|..:|...:::||:.:|   .:.|..||.
  Fly   128 FSSTIKAIGLASSNPANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIR 192

Human   178 QNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWI 237
            ..|:||...  |||:||||||||||.|..|.|:|||| ..|.....||||.:|....:|:
  Fly   193 STMICAAAS--GKDACQGDSGGPLVSGGVLVGVVSWG-YGCAYSNYPGVYADVAALRSWV 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	72/222 (32%)
gammaTry	NP_725034.1	Tryp_SPc	30..249	CDD:214473	72/224 (32%)