Protein Alignment KLK6 and thetaTry

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_523693.1
• Gene: thetaTry / 36218
• FlyBaseID: FBgn0011555
• Length: 262
• Species: Drosophila melanogaster
• Alignment Length: 265
• Identity: 88/265 - (33%)
• Similarity: 132/265 - (49%)
• Gaps: 38/265 - (14%)

Human     1 MKKLMVVLSLIAAAWA-------------EEQNKLVHGGPCDKTSHPYQAALYT-SGHLLCGGVL 51
            |.:|:|:|..:|...|             |.:.::|.|......:||||.:|.| ||...|||.|
  Fly     1 MHRLVVLLVCLAVGSACAGTVGVSNGDPFEREGRIVGGEDTTIGAHPYQVSLQTKSGSHFCGGSL 65

Human    52 IHPLWVLTAAHC----KKPNLQVFLGKHNLRQRESSQEQSSVVRAV----IHPDYDAASHDQDIM 108
            |:...|:|||||    |...:.|.||       .:...:..:|.||    .:.||::.:.:.|:.
  Fly    66 INEDTVVTAAHCLVGRKVSKVFVRLG-------STLYNEGGIVVAVRELAYNEDYNSKTMEYDVG 123

Human   109 LLRLARPAKLSELIQPLPLERDCSANTTSCHILGWGKTA---DGDFPDTIQCAYIHLVSREEC-- 168
            :|:|....|.:|.|:.:.|..:.....|:..:.|||...   ....|.|:|..|:::|..:.|
  Fly   124 ILKLDEKVKETENIRYIELATETPPTGTTAVVTGWGSKCYFWCMTLPKTLQEVYVNIVDWKTCAS 188

Human   169 -EHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCR 232
             |:.|...|..:|:||.::|  ||:|||||||||..|:.|.|:|||| ..|.|...||||::|..
  Fly   189 DEYKYGEIIYDSMVCAYEKK--KDACQGDSGGPLAVGNTLVGIVSWG-YACASNLLPGVYSDVPA 250

Human   233 YTNWI 237
            ...||
  Fly   251 LRKWI 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	79/228 (35%)
thetaTry	NP_523693.1	Tryp_SPc	34..255	CDD:214473	79/230 (34%)