Protein Alignment KLK6 and zetaTry

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_523691.1
• Gene: zetaTry / 36216
• FlyBaseID: FBgn0011556
• Length: 280
• Species: Drosophila melanogaster
• Alignment Length: 272
• Identity: 84/272 - (30%)
• Similarity: 123/272 - (45%)
• Gaps: 38/272 - (13%)

Human     4 LMVVLSLIAAAWA-------EEQN----KLVHGGPCDKTSHPYQAALYTSG---------HLLCG 48
            |..::||:|....       :|::    ::|.|...|....|||.:|...|         | .||
  Fly    10 LAFLVSLVALTQGLPLLEDLDEKSVPDGRIVGGYATDIAQVPYQISLRYKGITTPENPFRH-RCG 73

Human    49 GVLIHPLWVLTAAHC----KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPD-YDAASHDQDIM 108
            |.:.:...::|||||    .....:|..|.:  .|..|....::|...|:|.. |..|:::.||.
  Fly    74 GSIFNETTIVTAAHCVIGTVASQYKVVAGTN--FQTGSDGVITNVKEIVMHEGYYSGAAYNNDIA 136

Human   109 LLRLARPAKLSEL-IQPLPLERDCSANTTSCHILGWGKTADGDF-PDTIQCAYIHLVSREECEHA 171
            :|.:..|..|:.. |:.:.|..:.....|...:.|||.|:.|.: .:.:....:.:||.|.|:..
  Fly   137 ILFVDPPLPLNNFTIKAIKLALEQPIEGTVSKVSGWGTTSPGGYSSNQLLAVDVPIVSNELCDQD 201

Human   172 YPG------QITQNMLCAGDEKY-GKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTN 229
            |..      :||..|||||.... |.|:|||||||||...|.|.|:||||| .|.....||||.|
  Fly   202 YEDFGDETYRITSAMLCAGKRGVGGADACQGDSGGPLAVRDELYGVVSWGN-SCALPNYPGVYAN 265

Human   230 VCRYTNWIQKTI 241
            |.....||...:
  Fly   266 VAYLRPWIDAVL 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	77/236 (33%)
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	77/238 (32%)