Protein Alignment KLK6 and lambdaTry

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_610673.1
• Gene: lambdaTry / 36214
• FlyBaseID: FBgn0043470
• Length: 272
• Species: Drosophila melanogaster
• Alignment Length: 264
• Identity: 82/264 - (31%)
• Similarity: 135/264 - (51%)
• Gaps: 21/264 - (7%)

Human     1 MKKLMVVL-------SLIAAAWAEEQ-------NKLVHGGPCDKTSHPYQAALYTSGHLLCGGVL 51
            |.:::||.       ||....:..|:       .::|.|...:.|.:|:|.::...|:..|||.:
  Fly     1 MSRILVVFLVLGVGCSLADPIYRNEEVHIPKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTI 65

Human    52 IHPLWVLTAAHCKK-----PNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLR 111
            .....:::||||..     .||.:..|..|:......|::..|...:|||.|...::|.|..:|.
  Fly    66 YRSNQIISAAHCVNTLSGPENLTIVAGSSNIWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILI 130

Human   112 LARPAKLSELIQPLPLERDCSANTTSCHILGWGKTAD-GDFPDTIQCAYIHLVSREECEHAYPGQ 175
            |....:.::.:||:.|.::...:.|...:.|||.|:: |...|.:|...:::|....|::||...
  Fly   131 LDGDFEFNDAVQPIELAKERPDHDTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAYSIM 195

Human   176 ITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKT 240
            :|..|||||....|||:||||||||||..:.|.|:||||. .|..::.||||.:|....:|:.:|
  Fly   196 LTSRMLCAGVNGGGKDACQGDSGGPLVYNNTLLGIVSWGT-GCAREKYPGVYCSVPDVLDWLVET 259

Human   241 IQAK 244
            :..|
  Fly   260 VADK 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	73/219 (33%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	74/223 (33%)