Protein Alignment KLK6 and CG12133

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_610540.2
• Gene: CG12133 / 36036
• FlyBaseID: FBgn0033469
• Length: 340
• Species: Drosophila melanogaster
• Alignment Length: 265
• Identity: 75/265 - (28%)
• Similarity: 109/265 - (41%)
• Gaps: 50/265 - (18%)

Human    22 LVHGGPCDKTSHPYQAAL----YTSGHL---LCGGVLIHPLWVLTAAHCKKPN----LQVFLGKH 75
            :|.|........|:...|    ||:...   :|.|.||...:|||||||...|    .:|.||:|
  Fly    62 IVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASRYVLTAAHCLNVNDFYVARVRLGEH 126

Human    76 NLRQRESSQE-----QSSVVRAVIHPDYDA---ASHDQ----------DIMLLRLARPAKLSELI 122
            :   .|:..:     ..:.:.|..|.|.|.   ..|:|          ||.||||....|.:..|
  Fly   127 D---TENDPDYTWLPNGAKIWAPAHVDIDVDLRVPHEQYYTRNGRHYNDIALLRLKSRVKYTLQI 188

Human   123 QPLPLERDCSANTTS-----CHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQN--M 180
            :|:.:......:|:|     ..|.|||.:........::...|..:|.:||.:.||..:...  .
  Fly   189 RPICIWPGIELSTSSFKNFPFQIAGWGDSGLQQKSTVLRQGTISGMSPDECLNRYPTLLVDKDIQ 253

Human   181 LCA-GDEKYGKDSCQGDSGGPLVCG--------DHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNW 236
            :|| |.:  |.|:..||||.||:..        .:|.|:.|:|..|......|.|||....|..|
  Fly   254 ICAMGWD--GTDTGLGDSGSPLMASVGRGADQFYYLAGITSYGGGPSSYGYGPAVYTKTSSYYEW 316

Human   237 IQKTI 241
            |:|.|
  Fly   317 IKKKI 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	71/258 (28%)
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	71/259 (27%)