Protein Alignment KLK6 and CG1773

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_610512.1
• Gene: CG1773 / 35999
• FlyBaseID: FBgn0033439
• Length: 317
• Species: Drosophila melanogaster
• Alignment Length: 266
• Identity: 77/266 - (28%)
• Similarity: 128/266 - (48%)
• Gaps: 46/266 - (17%)

Human     6 VVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHL---LCGGVLIHPLWVLTAAHC---- 63
            |:.:||.|  ...:.::..|......|.|:.|.|:.||.:   .|||.|:..|:|||||||
  Fly    48 VLSNLIPA--QRLRRRITGGRKSSLLSQPWMAFLHISGDIEMCRCGGSLLSELFVLTAAHCFKMC 110

Human    64 -KKPNLQVFLGKHNLR----------QRESS--QEQSSVVRAVIHPDYDAASHDQDIMLLRLARP 115
             :...::|:||:.::.          ||..:  .|:.::.:.::|.:::......||.|::|.:.
  Fly   111 PRSKEIRVWLGELDISSTSDCVTYNYQRVCALPVEEFTIDKWILHEEFNLFYPGYDIALIKLNKK 175

Human   116 AKLSELIQP--LPLERDCSANT----TSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPG 174
            ....:.|:|  |||..:..|.|    .|...:|||:|....|.::..  .:| ::.|:|.   .|
  Fly   176 VVFKDHIRPICLPLTDELLAFTLQLGQSYMAVGWGRTESRRFANSTM--EVH-INTEKCT---DG 234

Human   175 QITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHL--------RGLVSWGNIPCGSKEKPGVYTNVC 231
            :.| :.|||..:..  |:|.|||||||:....|        .|:||.|:..||:.:| ..|.:|.
  Fly   235 RDT-SFLCANGDYV--DTCTGDSGGPLIWKTTLFGKARTVQFGVVSTGSQNCGAGQK-AYYMDVP 295

Human   232 RYTNWI 237
            .|..||
  Fly   296 TYVPWI 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	71/247 (29%)
CG1773	NP_610512.1	Tryp_SPc	61..301	CDD:214473	71/249 (29%)