Protein Alignment KLK6 and CG8172

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_001097235.2
• Gene: CG8172 / 35905
• FlyBaseID: FBgn0033362
• Length: 561
• Species: Drosophila melanogaster
• Alignment Length: 244
• Identity: 90/244 - (36%)
• Similarity: 126/244 - (51%)
• Gaps: 23/244 - (9%)

Human    20 NKLVHGGPCDKTSHPYQAALYTSGHLL----CGGVLIHPLWVLTAAHC----KKPNLQVFLGKHN 76
            |::|.|......|||:|.||..||.|.    |||.||...||:|||||    ...|:::.||:.:
  Fly   314 NRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHCVASTPNSNMKIRLGEWD 378

Human    77 LRQRES--SQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANT-TSC 138
            :|.:|.  :.|:..:.|..:||.|:.|....|:.|:||.|.....:.|.|:.|....:..| ...
  Fly   379 VRGQEERLNHEEYGIERKEVHPHYNPADFVNDVALIRLDRNVVYKQHIIPVCLPPSTTKLTGKMA 443

Human   139 HILGWGKTADGD--FPDTIQCAYIHLVSREECEHAYPG-----QITQNMLCAGDEKYGKDSCQGD 196
            .:.|||:|..|.  .|..:|...:.::|.:.|:..:..     .|....||||.:..|:||||||
  Fly   444 TVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHDVFLCAGYKDGGRDSCQGD 508

Human   197 SGGPLVC----GDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 241
            |||||..    ...|.|||||| |.||.:..||||||:.|:..||.|.:
  Fly   509 SGGPLTLTMDGRKTLIGLVSWG-IGCGREHLPGVYTNIQRFVPWINKVM 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	86/235 (37%)
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	88/239 (37%)