Protein Alignment KLK6 and Send1

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_608662.1
• Gene: Send1 / 33407
• FlyBaseID: FBgn0031406
• Length: 255
• Species: Drosophila melanogaster
• Alignment Length: 245
• Identity: 79/245 - (32%)
• Similarity: 117/245 - (47%)
• Gaps: 24/245 - (9%)

Human     6 VVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQV 70
            :::|.:.....|...:::.|...|.|..|:|.:|...|...|||.:.....::|||||.|.
  Fly    14 LLISPVVPVLLEPSERIIGGSSMDITDVPWQVSLQYYGEHFCGGSIYSKTIIITAAHCIKE---- 74

Human    71 FLGKHNLRQRESSQEQSSVVRAV----IHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDC 131
              |:.::|...|..:...||..|    |||.:|..:.:.|:.:|:|:.|...|:.||.:||....
  Fly    75 --GERSIRAGSSLHDSGGVVVGVEAYIIHPQFDKHNMENDVAVLKLSSPLSFSDSIQTIPLAETD 137

Human   132 SANTTSCHILGWGKTADGDF---PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSC 193
            ...::|....|||:   |:|   |..:|...|.:.....|:..|...:....:|||  :.||..|
  Fly   138 PPTSSSALATGWGR---GNFLIRPRQLQGVEILIRPLIVCKLKYGNGVFNEDICAG--RMGKGGC 197

Human   194 QGDSGGPLVCGDHLRGLVS-WGNIPC-GSKEKPGVYTNVCRYTNWIQKTI 241
            .||||||||....|.|:.| .|||.| ||    .:|.:|.||.|||...|
  Fly   198 YGDSGGPLVFNGQLVGITSRTGNIVCLGS----SLYASVARYRNWILSAI 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	74/222 (33%)
Send1	NP_608662.1	Tryp_SPc	29..239	CDD:214473	74/224 (33%)