Protein Alignment KLK6 and Ser12

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_523456.1
• Gene: Ser12 / 33406
• FlyBaseID: FBgn0011832
• Length: 245
• Species: Drosophila melanogaster
• Alignment Length: 258
• Identity: 81/258 - (31%)
• Similarity: 124/258 - (48%)
• Gaps: 41/258 - (15%)

Human     4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC-KKP- 66
            |:..::||:|..:.|  ::|.|.|...:..|:||||..|...:||.|:.....::||||| ::|
  Fly     8 LVASVTLISAGSSPE--RIVGGHPVLISEVPWQAALMYSEKYICGAVIYSDKIIITAAHCVERPF 70

Human    67 -------------NLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAAS-HDQDIMLLRLARPAK 117
                         ||.   |:|         .:.:|:|.  |.||.::: ...||.::||.....
  Fly    71 DTLYSVRVGSVWKNLG---GQH---------ARVAVIRK--HEDYVSSTILFNDIAVIRLVDTLI 121

Human   118 LSELIQPLPLERDCSANTTSCHILGWGKTADGDF---PDTIQCAYIHLVSREECEHAYPGQITQN 179
            .:..::|:.|.....|..|...:.|||:.  |..   |.::....:.::....|:.:|. .||:.
  Fly   122 FNAEVRPIQLADSAPAAGTEASVSGWGEI--GILWLQPTSLLKTSVKILDPNVCKRSYQ-YITKT 183

Human   180 MLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 242
            |:||.  ...||||.||||||||.|..|.|:||:| |.|.:...||||.||.....||...|:
  Fly   184 MICAA--ALLKDSCHGDSGGPLVSGGQLVGIVSYG-IGCANPFFPGVYANVAELKPWILNAIE 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	73/232 (31%)
Ser12	NP_523456.1	Tryp_SPc	23..238	CDD:214473	73/234 (31%)