Protein Alignment KLK6 and CG11911

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_608518.1
• Gene: CG11911 / 33206
• FlyBaseID: FBgn0031249
• Length: 277
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 84/267 - (31%)
• Similarity: 126/267 - (47%)
• Gaps: 31/267 - (11%)

Human     1 MKKLMV--VLSLIAAA-WAEEQNKL------------VHGGPCDKTSHPYQAALYTS----GHLL 46
            ||.:.|  |::|:||| .|:..:||            ::|...:..|.||..:|.|:    .| :
  Fly     1 MKLITVTLVIALVAAAQGAKLSDKLAKLVPSFATGFVINGTEAEPHSAPYIVSLATNYLKHSH-I 64

Human    47 CGGVLIHPLWVLTAAHC-KKP-NLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIML 109
            |||.||:..|::||||| .:| .:.:..|.|...:.:...:|..|....:|..|.......||.|
  Fly    65 CGGTLINKDWIVTAAHCISEPVGMSIIAGLHTRAEVDELTQQRQVDFGRVHEKYTGGVGPYDIAL 129

Human   110 LRLARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAY 172
            |.:......:|.:||..|......:....|:.|||:.....|  ..|:|.....:::.|||:...
  Fly   130 LHVNESFIFNEWVQPATLPSREQVHEGETHLYGWGQPKSYIFSGAKTLQTVTTQILNYEECKEEL 194

Human   173 P--GQITQNMLCAGDEKYGKDSCQGDSGGPLV-----CGDHLRGLVSWGNIPCGSKEKPGVYTNV 230
            |  ..|.::.:|:...:..|.:|.||||||||     ....|.|:||||.||||....|.:||.|
  Fly   195 PESAPIAESNICSSSLQQSKSACNGDSGGPLVVEFTNAPSELIGIVSWGYIPCGLANMPSIYTKV 259

Human   231 CRYTNWI 237
            ..|.:||
  Fly   260 SAYIDWI 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	71/228 (31%)
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	71/229 (31%)