Protein Alignment KLK6 and CG11912

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_608517.1
• Gene: CG11912 / 33205
• FlyBaseID: FBgn0031248
• Length: 271
• Species: Drosophila melanogaster
• Alignment Length: 273
• Identity: 80/273 - (29%)
• Similarity: 120/273 - (43%)
• Gaps: 31/273 - (11%)

Human     1 MKKLMVVLSLIAAAWAE--------EQNKLVHGGPCDKTSHPYQAALY-TSGHLLCGGVLIHPLW 56
            ||:..|:.:|..|:.:.        .:.::::|....|...||..:|. ||....|.|.|:..:.
  Fly     1 MKQFAVIFALALASVSAISVPQPGFPEGRIINGYEAAKGEAPYIVSLQTTSNSHFCAGSLLDEVT 65

Human    57 VLTAAHCKKPNL-QVFLGKHNLRQRESSQ-EQSSVVRAVIHPDYDAASHDQDIMLLRL------- 112
            ::|||||...|. |...|.|:...:|:.| .:.:..:.|||.:|.......||.|:.|
  Fly    66 IVTAAHCLTYNQGQAVAGAHSRTDQENVQIRKFTNAQYVIHENYGGGVGPNDIGLILLKEEDAFD 130

Human   113 ----ARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYP 173
                ||..  |..:..:.|.......|:..::.|||:...|..|..:|.....:|...||:.|.|
  Fly   131 LNAVARDG--SNPVSAVSLPSKTFQGTSDGYLYGWGRDNSGLLPLNLQKLDAIIVDYNECKAALP 193

Human   174 --GQITQNMLCAGDEKYGKDSCQGDSGGPLVC-----GDHLRGLVSWGNIPCGSKEKPGVYTNVC 231
              ..:.:..:|.........||.||||||||.     |..|.|:||||..||.|...|.|||:|.
  Fly   194 SNNSLAETNVCTHTPGKADGSCNGDSGGPLVSQSSSRGAELIGIVSWGYTPCLSTTYPSVYTSVS 258

Human   232 RYTNWIQKTIQAK 244
            .:..||.:..:||
  Fly   259 SFLPWIDENRKAK 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	71/234 (30%)
CG11912	NP_608517.1	Tryp_SPc	29..264	CDD:214473	71/236 (30%)