Protein Alignment KLK6 and CG9673

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_573149.1
• Gene: CG9673 / 32649
• FlyBaseID: FBgn0030775
• Length: 261
• Species: Drosophila melanogaster
• Alignment Length: 263
• Identity: 81/263 - (30%)
• Similarity: 119/263 - (45%)
• Gaps: 38/263 - (14%)

Human     5 MVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAAL-YTSGHLLCGGVLIHPLWVLTAAHC----- 63
            :::..||.:|.|..|.:::.|....:..:|:.|:: |...| :|.|.:|....:||||||
  Fly    12 LLIFGLILSAEASPQGRILGGEDVAQGEYPWSASVRYNKAH-VCSGAIISTNHILTAAHCVSSVG 75

Human    64 ----KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP 124
                ....|.|.||..|.....|.....||   :|||.|....|  ||.:|.|......|:.||.
  Fly    76 ITPVDASTLAVRLGTINQYAGGSIVNVKSV---IIHPSYGNFLH--DIAILELDETLVFSDRIQD 135

Human   125 LPL-------ERDCSA---NTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECE----HAYPGQ 175
            :.|       ..|..|   |.|..::.|||:.:||......|.|..:.:||..||    :.|
  Fly   136 IALPPTTDEETEDVDAELPNGTPVYVAGWGELSDGTASYKQQKANYNTLSRSLCEWEAGYGY--- 197

Human   176 ITQNMLCAGDEKYGKDSCQGDSGGPLVCGDH-LRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQK 239
              ::::|....: |:..|:||:|..::..|. ||||.|:...||||| .|.|.|.|..|..||:.
  Fly   198 --ESVVCLSRAE-GEGICRGDAGAAVIDDDKVLRGLTSFNFGPCGSK-YPDVATRVSYYLTWIEA 258

Human   240 TIQ 242
            ..|
  Fly   259 NTQ 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	73/238 (31%)
CG9673	NP_573149.1	Tryp_SPc	28..256	CDD:214473	73/240 (30%)