Protein Alignment KLK6 and CG8952

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_573072.1
• Gene: CG8952 / 32525
• FlyBaseID: FBgn0030688
• Length: 276
• Species: Drosophila melanogaster
• Alignment Length: 272
• Identity: 75/272 - (27%)
• Similarity: 117/272 - (43%)
• Gaps: 46/272 - (16%)

Human     2 KKLMVVLSLIAAAWAEEQ-------------NKLVHGGPCDKTSHPYQAALYTSG--HLLCGGVL 51
            :.||:|  |:||.....|             |::|.|........|:|..|....  .|||||.:
  Fly     7 RSLMLV--LLAAISVVGQPFDPANSSPIKIDNRIVSGSDAKLGQFPWQVILKRDAWDDLLCGGSI 69

Human    52 IHPLWVLTAAHCKKPNLQVFL--GKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLAR 114
            |...||||||||......:||  |..:|....:....|:.:  :|||||:...:: |:.|::|..
  Fly    70 ISDTWVLTAAHCTNGLSSIFLMFGTVDLFNANALNMTSNNI--IIHPDYNDKLNN-DVSLIQLPE 131

Human   115 PAKLSELIQPLPL------ERDCSANTTSCHILGWGKTADG--DFPDTIQCAYIHLVSREECEHA 171
            |...|..||.:.|      ..|...:..:  |.|:|.|.|.  |:.:|:..|.:.::...:|...
  Fly   132 PLTFSANIQAIQLVGQYGDSIDYVGSVAT--IAGFGYTEDEYLDYSETLLYAQVEIIDNADCVAI 194

Human   172 YPGQ--ITQNMLCA-GDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGS--------KEKPG 225
            | |:  :..:.:|| |.:.....:|.|||||||:.  :.:.:..|..|...|        ...|.
  Fly   195 Y-GKYVVVDSTMCAKGFDGSDMSTCTGDSGGPLIL--YNKTIQQWQQIGINSFVAEDQCTYRLPS 256

Human   226 VYTNVCRYTNWI 237
            .|..|..:..:|
  Fly   257 GYARVSSFLGFI 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	66/236 (28%)
CG8952	NP_573072.1	Tryp_SPc	37..268	CDD:214473	66/238 (28%)