Protein Alignment KLK6 and CG33127

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_787956.1
• Gene: CG33127 / 318893
• FlyBaseID: FBgn0053127
• Length: 284
• Species: Drosophila melanogaster
• Alignment Length: 284
• Identity: 79/284 - (27%)
• Similarity: 120/284 - (42%)
• Gaps: 55/284 - (19%)

Human     4 LMVVLSLIAAA----------------WAEEQNKLVHGGPCDKTSH-PYQAAL------YTSGHL 45
            |:.:|:|..||                .||.|..::.|.......: ||..:|      ||.
  Fly     7 LLPLLALAGAAKLPHIQHLTLRDTEQVHAEIQPLIIDGYDVQGVDNVPYLVSLSLTRATYTH--- 68

Human    46 LCGGVLIHPLWVLTAAHC---------KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAA 101
            |||..:|...|:||||||         ......|:.|..| |...::.:...|..|..|..::..
  Fly    69 LCGASIIGKRWLLTAAHCVDELRTFNGDAVGTPVYAGIIN-RSNVTAAQVRYVDFASTHRSFNGN 132

Human   102 SHDQDIMLLRLARPAKLSELIQPLPL---ERDCSANTTSCHILGWGKT-ADGD-FPDTIQCAYIH 161
            :...:|.||.::...:.:..:|.:.|   ..|.|..|.:.:  |||.| .||| :...:|.|:..
  Fly   133 AGSDNIALLHVSESFEYNARVQQIALPDINDDYSNKTAAAY--GWGLTDPDGDEYSKELQYAFAP 195

Human   162 LVSREECEHAYPGQ--ITQNMLCAGDEKYGKDSCQGDSGGPLVCGD-----HLRGLVSWGNIPCG 219
            |::...|:...|..  :|...:|:..:     :|.||.|.||:...     .|.||.||..:|||
  Fly   196 LLNSTGCKELLPADAPLTAQQVCSQVK-----TCYGDGGTPLIYWPITGPAELVGLGSWSYMPCG 255

Human   220 SKEKPGVYTNVCRYTNWIQKTIQA 243
            ...:|.|||:|..|..||.:||.|
  Fly   256 YANRPTVYTSVPPYIGWIHQTIGA 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	66/241 (27%)
CG33127	NP_787956.1	Tryp_SPc	41..273	CDD:214473	66/242 (27%)