Protein Alignment KLK6 and CG3795

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_569939.2
• Gene: CG3795 / 31128
• FlyBaseID: FBgn0025378
• Length: 305
• Species: Drosophila melanogaster
• Alignment Length: 272
• Identity: 75/272 - (27%)
• Similarity: 112/272 - (41%)
• Gaps: 42/272 - (15%)

Human     5 MVVLSLIAAAWAEEQNKLVHGGPCDKTSHP--YQAALYTSGHL---------------------- 45
            ::::|:.|.:.:|.|...:|..|..:...|  :| .|.|.|:.
  Fly    10 ILLISVSANSNSESQAGQLHSAPSQRQDRPSDFQ-FLVTGGYRPDTNDLVKYTVSLRMGKPKKFF 73

Human    46 ----LCGGVLIHPLWVLTAAHC--------KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDY 98
                .|.|.:.....:||||||        |...|.|..|......:.|:.:.......:.||.|
  Fly    74 GDNHFCAGTIFSERAILTAAHCMFSNRRKLKAKKLMVVAGTPRRLLKSSTTQIIEAEELLPHPKY 138

Human    99 -DAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCHILGWGKTAD-GDFPDTIQCAYIH 161
             ...|...||.|:.|.....|.:.:..:||..........|.|:|||.... |..||......:.
  Fly   139 KKGKSQKYDIGLILLEADLSLGDAVAKIPLYNKVPVAGAPCSIVGWGTVIQFGPLPDEAINGDMQ 203

Human   162 LVSREECEHAYPGQITQNMLCAGDEKYGK-DSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPG 225
            ::....||... |.....||||.|:.... |||||||||||:|.:.:.|:||:| :.||..:..|
  Fly   204 ILPDTFCEKLL-GWSNAGMLCANDKHDSDVDSCQGDSGGPLICDNMVTGIVSFG-MGCGEPDSAG 266

Human   226 VYTNVCRYTNWI 237
            :||:|..:.:||
  Fly   267 IYTDVYHFRDWI 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	69/252 (27%)
CG3795	NP_569939.2	Tryp_SPc	60..281	CDD:238113	64/221 (29%)