Protein Alignment KLK6 and CG11664

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_569865.1
• Gene: CG11664 / 31033
• FlyBaseID: FBgn0040341
• Length: 254
• Species: Drosophila melanogaster
• Alignment Length: 254
• Identity: 63/254 - (24%)
• Similarity: 109/254 - (42%)
• Gaps: 30/254 - (11%)

Human     1 MKKLMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKK 65
            ::.|.::|..||..|.:   .|..|.|..:.::.|...:| ....|..|.|....:|||.|||.|
  Fly     5 VESLQLILLAIAVRWGD---ALHRGIPVQQQNYGYVMQIY-GPQFLAAGSLFSARYVLTVAHCFK 65

Human    66 PN-----LQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPL 125
            .|     |.|..|...:......::.:.::|   ||.:...:...||.:||:......|.:|..:
  Fly    66 KNTKPEELSVRAGYRWIAWEFRGKQVAGLLR---HPKFSPLTLRNDIAVLRVKAAISHSHMINYI 127

Human   126 PLERDCSANTTSCH-------ILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCA 183
            .|   ||...|..:       :.||...   .....::...:.:...:.|...:| ||:..::||
  Fly   128 GL---CSRPLTPLNMFAPPQELAGWNLM---HIAQPLKSMSVQVEPEKNCRQWFP-QISGGVICA 185

Human   184 GDEKYGKDSCQGDSGGPLVCGDHLRGL-VSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 241
             ....|:..|.||||.||:.|..:.|| :::..  ||.|..|.::|:|..:..:|.:.:
  Fly   186 -SATMGEGLCYGDSGDPLISGGEVCGLAIAFRK--CGDKRYPALFTDVHYHRAFIAQAV 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	56/226 (25%)
CG11664	NP_569865.1	Tryp_SPc	38..239	CDD:473915	54/214 (25%)