Protein Alignment KLK6 and CG43336

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_001247122.1
• Gene: CG43336 / 12798414
• FlyBaseID: FBgn0263041
• Length: 279
• Species: Drosophila melanogaster
• Alignment Length: 243
• Identity: 75/243 - (30%)
• Similarity: 111/243 - (45%)
• Gaps: 34/243 - (13%)

Human    21 KLVHGGPCDKTSHPYQAALY-TSGHLLCGGVLIHPLWVLTAAHC--KKPNLQVFLGKHNLRQRES 82
            ::.:|.....||.|:.|.|: |.|..:|||.||....|||||||  .:..|...||:::..:.|.
  Fly    37 RVKNGTVASLTSSPWMAFLHSTDGRFICGGSLITNRLVLTAAHCFLDRTELVARLGEYDREEYEM 101

Human    83 SQE-------QSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPL-----PLERDCSANT 135
            ..:       ::.|.|...|..|:..:...||.:|||.|..:.::.|:|:     |..|....:.
  Fly   102 CHDSYCTYRIEAMVERGFRHRHYNPMTMAYDIAILRLYRKVQYTDNIRPICIVIDPRWRKYIDSL 166

Human   136 TSCHILGWGKT-ADGDFPD--TIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDS 197
            ......||||| ::||...  |:..|..|   .|.|.......:|.|..|||:|:  .:.|.|||
  Fly   167 DPLTGTGWGKTESEGDSAKLRTVDLARKH---PEVCRRYATLSLTANQFCAGNER--SNLCNGDS 226

Human   198 GGP----LVCGDHLR----GLVSWGNIPCGSKEKPGVYTNVCRYTNWI 237
            |||    :..|...|    |:.|:.|..|   ....|:|:|..|.:||
  Fly   227 GGPVGALIPYGKSKRFVQVGIASFTNTQC---VMVSVFTDVMSYVDWI 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	73/239 (31%)
CG43336	NP_001247122.1	Tryp_SPc	37..271	CDD:214473	73/241 (30%)