Protein Alignment KLK6 and CG43110

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 236
• Identity: 73/236 - (30%)
• Similarity: 118/236 - (50%)
• Gaps: 21/236 - (8%)

Human    21 KLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKK-PNLQVFLGKHNLRQRESSQ 84
            |::.|....:.|..|.|.::.:.||||||.:||..:|||.||||. ..|.|.||.:|:..   ..
  Fly    35 KIISGSNASQQSAQYMAGIFNTTHLLCGGTIIHEDFVLTVAHCKSTQTLFVRLGAYNINH---PT 96

Human    85 EQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCS--ANTTSCHILGWGKTA 147
            :|..|:..:.||.|..:::..||.|::|.|....:..|||:.:..|.:  ......:..|||:|.
  Fly    97 DQIRVIETIAHPQYSNSTYANDIALVKLERSVIFNLNIQPICIHLDATLGKQIRYYNAFGWGRTR 161

Human   148 DGDFPDTIQCAYIHLVSREECEHAYPGQITQ-NMLCAGDEKYGKDSCQGDSGGPLVCG------- 204
            :.:..|.:|..:::..:...| |.|.|.... ..:||..::  .|:|.|||||||:..
  Fly   162 NAEQSDILQRIFVNRTNPMIC-HLYLGMSPDPKQICATTDQ--GDTCAGDSGGPLISKITYQGKN 223

Human   205 -DHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQAK 244
             |...|:.|:|...|..   .|:||:|.:|:.||...:::|
  Fly   224 FDTQFGITSYGTRECNG---VGLYTDVSQYSGWIANIVRSK 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	69/225 (31%)
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	71/229 (31%)