Protein Alignment PRSS8 and CG10405

DIOPT Version :10

• Sequence 1: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Sequence 2: NP_001036717.1
• Gene: CG10405 / 41996
• FlyBaseID: FBgn0038431
• Length: 268
• Species: Drosophila melanogaster
• Alignment Length: 276
• Identity: 93/276 - (33%)
• Similarity: 134/276 - (48%)
• Gaps: 28/276 - (10%)

Human    15 VAILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQW 79
            :..||..|:|.. ..|...||.....|.:||..|..|..||:|:|:|:..:.||:||.|::|..|
  Fly     8 IPFLLIAGILVI-LEASRTEAAVPRQPDSRIVNGREATEGQFPYQLSLRRQTVHICGASILSSNW 71

Human    80 VLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQ----- 139
            .::||||... |.::..|..|....: ..:....|..:|.|..||:|.:.....|:|||:
  Fly    72 AITAAHCIDG-HEQQPREFTLRQGSI-MRTSGGTVQPVKAIYKHPAYDRADMNFDVALLRTADGA 134

Human   140 LSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETC-NC 203
            ||.|:   ..:.||.||....:....:...|:||||::.|..:|: ..|:...|..:::|.| |.
  Fly   135 LSLPL---GKVAPIRLPTVGEAISESMPAVVSGWGHMSTSNPVLS-SVLKSTTVLTVNQEKCHND 195

Human   204 LYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRP 268
            |.:...       |.|.|.||  .....||||||||||:|  .:|.  |.||||||..|.....|
  Fly   196 LRHHGG-------VTEAMFCA--AARNTDACQGDSGGPIS--AQGT--LIGIVSWGVGCADPYYP 247

Human   269 GVYTLAS--SYASWIQ 282
            ||||..:  :...||:
  Fly   248 GVYTRLAHPTIRRWIR 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	84/246 (34%)
CG10405	NP_001036717.1	Tryp_SPc	36..262	CDD:214473	83/244 (34%)