Protein Alignment PRSS8 and Sb

DIOPT Version :10

• Sequence 1: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Sequence 2: NP_476709.1
• Gene: Sb / 41958
• FlyBaseID: FBgn0003319
• Length: 787
• Species: Drosophila melanogaster
• Alignment Length: 290
• Identity: 100/290 - (34%)
• Similarity: 152/290 - (52%)
• Gaps: 34/290 - (11%)

Human    10 GQLGAVAILLYLGLLRSGTGAEGAEAPCGV----APQARITGGSSAVAGQWPWQVSIT------Y 64
            |.||.|..:            ..|.:.|||    .|:.||.||.||..|:||||||:.      :
  Fly   517 GALGHVKTI------------SAARSECGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFGF 569

Human    65 EGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSED---AKVSTLKDIIPHPSY 126
            ...|.|||:|::|.|:.:|.||. .:.......:::|.:......|.   .:....|.:: ||.|
  Fly   570 SSTHRCGGALINENWIATAGHCV-DDLLISQIRIRVGEYDFSHVQEQLPYIERGVAKKVV-HPKY 632

Human   127 LQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQL 191
            .....:.|:||::|.:|:.|:.::.|||||..: |...|::.||||||.::...:|  |..||::
  Fly   633 SFLTYEYDLALVKLEQPLEFAPHVSPICLPETD-SLLIGMNATVTGWGRLSEGGTL--PSVLQEV 694

Human   192 EVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSC-PVEGLWYLTGI 255
            .||::|.:.|..::....:.|   |:.:..:||||..||:|:|||||||||.. ..:|.::|.||
  Fly   695 SVPIVSNDNCKSMFMRAGRQE---FIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGI 756

Human   256 VSWGDACGARNRPGVYTLASSYASWIQSKV 285
            :|||..|...|.|||.|..|.:..||...|
  Fly   757 ISWGIGCAEANLPGVCTRISKFTPWILEHV 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	89/248 (36%)
Sb	NP_476709.1	Tryp_SPc	544..785	CDD:238113	89/248 (36%)