DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment PRSS8 and CG10472

DIOPT Version :9

Sequence 1:NP_002764.1 Gene:PRSS8 / 5652 HGNCID:9491 Length:343 Species:Homo sapiens
Sequence 2:NP_648017.1 Gene:CG10472 / 38688 FlyBaseID:FBgn0035670 Length:290 Species:Drosophila melanogaster


Alignment Length:254 Identity:85/254 - (33%)
Similarity:129/254 - (50%) Gaps:24/254 - (9%)


- Green bases have known domain annotations that are detailed below.


Human    41 PQARITGGSSAVAGQWPWQVSITY---EGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGA 102
            |..|||||..|...|:|:||.:..   .|...|||:::|::|:::||||  ::......:|.|||
  Fly    43 PSGRITGGQIAEPNQFPYQVGLLLYITGGAAWCGGTIISDRWIITAAHC--TDSLTTGVDVYLGA 105

Human   103 HQLDSYSEDAK----VSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFP 163
            |...:..|:.:    |.| |::|.|..::.|....||:|::|..||.|::||:|..||..:.|:.
  Fly   106 HDRTNAKEEGQQIIFVET-KNVIVHEDWIAETITNDISLIKLPVPIEFNKYIQPAKLPVKSDSYS 169

Human   164 --NGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGY 226
              .|.:...:|||.::.|.:..| ..||...||:::...|:..|.        ..|....:|. .
  Fly   170 TYGGENAIASGWGKISDSATGAT-DILQYATVPIMNNSGCSPWYF--------GLVAASNICI-K 224

Human   227 VEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGAR-NRPGVYTLASSYASWIQSK 284
            ..||...|.|||||||... :|...|.|..|:|.|.|.. ..|||:|..:.|..||:.|
  Fly   225 TTGGISTCNGDSGGPLVLD-DGSNTLIGATSFGIALGCEVGWPGVFTRITYYLDWIEEK 282

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PRSS8NP_002764.1 Tryp_SPc 44..281 CDD:214473 81/246 (33%)
Tryp_SPc 45..284 CDD:238113 82/248 (33%)
CG10472NP_648017.1 Tryp_SPc 46..279 CDD:214473 81/246 (33%)
Tryp_SPc 47..282 CDD:238113 82/248 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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