Protein Alignment PRSS8 and Send1

DIOPT Version :10

• Sequence 1: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Sequence 2: NP_608662.1
• Gene: Send1 / 33407
• FlyBaseID: FBgn0031406
• Length: 255
• Species: Drosophila melanogaster
• Alignment Length: 284
• Identity: 91/284 - (32%)
• Similarity: 127/284 - (44%)
• Gaps: 57/284 - (20%)

Human    17 ILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVL 81
            :||.:.||.|..      .|..:.|..||.||||......|||||:.|.|.|.||||:.|:..::
  Fly     8 LLLAVHLLISPV------VPVLLEPSERIIGGSSMDITDVPWQVSLQYYGEHFCGGSIYSKTIII 66

Human    82 SAAHCFPSEHHKEA-YEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPIT 145
            :||||.     ||. ..::.|:...||   ...|..::..|.||.:.:...:.|:|:|:||.|::
  Fly    67 TAAHCI-----KEGERSIRAGSSLHDS---GGVVVGVEAYIIHPQFDKHNMENDVAVLKLSSPLS 123

Human   146 FSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEV---PLISRETCNCLYNI 207
            ||..|:.|  |.|....|.......||||.   ...|:.|:.||.:|:   |||   .|...|.
  Fly   124 FSDSIQTI--PLAETDPPTSSSALATGWGR---GNFLIRPRQLQGVEILIRPLI---VCKLKYG- 179

Human   208 DAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPG--- 269
                   :.|..:.:|||.:  ||..|.|||||||             |..|...|..:|.|
  Fly   180 -------NGVFNEDICAGRM--GKGGCYGDSGGPL-------------VFNGQLVGITSRTGNIV 222

Human   270 -----VYTLASSYASWIQSKVTEL 288
                 :|...:.|.:||.|.:..|
  Fly   223 CLGSSLYASVARYRNWILSAIDVL 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	81/250 (32%)
Send1	NP_608662.1	Tryp_SPc	29..239	CDD:214473	80/248 (32%)