DRSC/TRiP Functional Genomics Resources

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Protein Alignment MASP1 and CG34437

DIOPT Version :9

Sequence 1:XP_011511291.1 Gene:MASP1 / 5648 HGNCID:6901 Length:735 Species:Homo sapiens
Sequence 2:NP_001097955.1 Gene:CG34437 / 5740179 FlyBaseID:FBgn0085466 Length:266 Species:Drosophila melanogaster


Alignment Length:262 Identity:63/262 - (24%)
Similarity:109/262 - (41%) Gaps:72/262 - (27%)


- Green bases have known domain annotations that are detailed below.


Human   469 PWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHD-- 531
            ||.|.|    .|...|    .||.|::..:::|.|..:..|...           ||:||..|  
  Fly    41 PWMAFI----ASPTKN----CSGTLINKQYVITTASCVFDQSES-----------TVFLGRFDNI 86

Human   532 VRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGL 596
            .::::..|..|...|..|..:|.|.:.|||||:.|.:||.....:.|:|:           .||.
  Fly    87 PQNRNRYVKHSVQSVYTHKLYNKQTFEHDIALLLLDDPVTFKMSIQPICI-----------WLGE 140

Human   597 VAG--------WGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTEN 653
            :..        ||:|      :::|.....|:. :|:..|        |:.|:     ..::.::
  Fly   141 ITNLNHLESNRWGLS------EKMIFQRINTVK-ILKIKK--------CRDSF-----GITLKKS 185

Human   654 MFCAGYYEGGKDTCLGDSGGAFVIFDDLSQR-W-VVQGLVSWGGPEECGSKQVYGVYTKVSNYVD 716
            ..|||:..|...|   ::|.:.|.....|.: | .:.|:.|:|..|.|       :|.|:::|:|
  Fly   186 QICAGFQNGNICT---ETGSSLVKQIHYSGKLWNTLIGIQSYGVSERC-------IYNKIAHYID 240

Human   717 WV 718
            |:
  Fly   241 WI 242

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MASP1XP_011511291.1 CUB 35..144 CDD:238001
FXa_inhibition 160..188 CDD:291342
CUB 192..301 CDD:278839
Sushi 308..369 CDD:278512
CCP 374..439 CDD:153056
Tryp_SPc 456..718 CDD:214473 62/260 (24%)
Tryp_SPc 457..718 CDD:238113 62/260 (24%)
CG34437NP_001097955.1 Tryp_SPc 39..242 CDD:214473 62/260 (24%)
Tryp_SPc 39..242 CDD:304450 62/260 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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