DRSC/TRiP Functional Genomics Resources

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Protein Alignment MASP1 and CG11670

DIOPT Version :9

Sequence 1:XP_011511291.1 Gene:MASP1 / 5648 HGNCID:6901 Length:735 Species:Homo sapiens
Sequence 2:NP_001368950.1 Gene:CG11670 / 41608 FlyBaseID:FBgn0038114 Length:431 Species:Drosophila melanogaster


Alignment Length:294 Identity:82/294 - (27%)
Similarity:132/294 - (44%) Gaps:65/294 - (22%)


- Green bases have known domain annotations that are detailed below.


Human   460 GRN-AEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVIPVSKEHV 523
            ||: ..||.:|..|.:...:.:...:.|.  .|:|:|..::|||||.|.:......::.:.    
  Fly   172 GRSIVAPGQYPHMAALGFRNENHEIDYKC--GGSLISEEFVLTAAHCLTTHGTSPDIVKIG---- 230

Human   524 TVYLGLHDVRDKSGAVNSS-----AARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPR 583
                   |::.|...:|.:     .|::.|||.:|.....|||.|:||..||.....|.||   |
  Fly   231 -------DIKLKEWELNVAPQRRRVAQIYLHPLYNASLNYHDIGLIQLNRPVEYTWFVRPV---R 285

Human   584 LEPEGPAP----HMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESR 644
            |.|....|    |.:| ....|.:.|.              :::|..:.|.|||..:|.:|..:.
  Fly   286 LWPMNDIPYGKLHTMG-YGSTGFAQPQ--------------TNILTELDLSVVPIEQCNSSLPAD 335

Human   645 SGN-YSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQ-----------RWVVQGLVSWGGPE 697
            .|: :.:..:..||..||..:|||.|||||...:  :|.:           |:.:.|:.|:|.  
  Fly   336 EGSPHGLLTSQICAHDYEKNRDTCQGDSGGPLQL--NLERRRRRHTSRKHYRYYLVGITSYGA-- 396

Human   698 ECGSKQVYGVYTKVSNYVDWVWEQMGLPQSVVEP 731
            .|.| ::.||||:||:|:||:       .|:|.|
  Fly   397 YCRS-ELPGVYTRVSSYIDWI-------ASIVWP 422

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MASP1XP_011511291.1 CUB 35..144 CDD:238001
FXa_inhibition 160..188 CDD:291342
CUB 192..301 CDD:278839
Sushi 308..369 CDD:278512
CCP 374..439 CDD:153056
Tryp_SPc 456..718 CDD:214473 78/279 (28%)
Tryp_SPc 457..718 CDD:238113 78/279 (28%)
CG11670NP_001368950.1 Tryp_SPc 172..419 CDD:238113 79/289 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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