DRSC/TRiP Functional Genomics Resources

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Protein Alignment PRPS1 and CG7024

DIOPT Version :10

Sequence 1:NP_002755.1 Gene:PRPS1 / 5631 HGNCID:9462 Length:318 Species:Homo sapiens
Sequence 2:NP_572182.1 Gene:CG7024 / 31407 FlyBaseID:FBgn0029722 Length:479 Species:Drosophila melanogaster


Alignment Length:68 Identity:15/68 - (22%)
Similarity:30/68 - (44%) Gaps:10/68 - (14%)


- Green bases have known domain annotations that are detailed below.


Human   193 HKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTI-----CHAADKLLSAGATRVYAILTHGI 252
            :||||    :.....:.:.::.||:.:.....:|.::     |||...|:......:.|.| .|:
  Fly    84 YKERK----IRGFCHLYNGQEAVAVGMKQRLRSCDSVITAYRCHAWTYLMGVSLYEIMAEL-FGV 143

Human   253 FSG 255
            .:|
  Fly   144 RTG 146

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PRPS1NP_002755.1 PrsA 1..314 CDD:440230 15/68 (22%)
Binding of phosphoribosylpyrophosphate. /evidence=ECO:0000255 212..227 2/14 (14%)
CG7024NP_572182.1 TPP_enzymes 37..381 CDD:470272 15/68 (22%)

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