Protein Alignment SLC7A10 and CG1607

DIOPT Version :10

• Sequence 1: XP_011525421.1
• Gene: SLC7A10 / 56301
• HGNCID: 11058
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_001263139.1
• Gene: CG1607 / 43707
• FlyBaseID: FBgn0039844
• Length: 507
• Species: Drosophila melanogaster
• Alignment Length: 633
• Identity: 206/633 - (32%)
• Similarity: 312/633 - (49%)
• Gaps: 147/633 - (23%)

Human     9 SGRGNPRPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVG 73
            :|.|:.....:.....|...|..| |.||.::.||:.||:|:|:|||||||:||.|||.::|||.
  Fly    19 NGNGDASAKLTNGDGDGGGDGGGE-VTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGSVN 82

Human    74 LALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVI 138
            |||.|||:.|..:.:|:.||||||..|.|||.||||:.|.||....|:.||...:|:.|.|.|::
  Fly    83 LALIVWVISGLFSMVGAYCYAELGTMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIV 147

Human   139 SMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIG 203
            ::|||.|||:|.||.|.||..::|:|::.|:::||.:|...|:|||.:||:||..|||||.:||.
  Fly   148 ALTFSTYVLKPFFPECTPPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIA 212

Human   204 VGLLQIFQGHFEELRPSNAFAFWMTPS-VGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPR 267
            .|:.|::.|:      :..|.|..|.: |..:||:|..|.||::|||:||::.||:.|..|||||
  Fly   213 TGVYQLYLGN------TQYFTFENTDTKVTSIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPR 271

Human   268 AIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVVSGPLLGPWLLPRPLPRPYTWPLYCAHP 332
            ||.||..|||.||...|::::|.:||.|::.|:||||....
  Fly   272 AIAISCTLVTIVYVMANVSFYTILSPDEVMGSSAVAVTYAE------------------------ 312

Human   333 DLRGEAAGLLFLGHACLRGSVNLRRDQW-LPVHLLQVTALGRRGHGEGRLGCRCAPVMPWARGRD 396
                .|.|:|                .| :||.:    ||...|...|
  Fly   313 ----RAFGML----------------AWTIPVFV----ALSTFGAVNG----------------- 336

Human   397 TCRGRGLPEAGMMIPHGNKCLITTGRQRKQEAGRLDEGENCPVGLLGPEQEVRGDSLRGTSGPKL 461
                                                                             
  Fly   337 ----------------------------------------------------------------- 336

Human   462 RPRMWPVPISVPNARLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLIN 526
                    |.:.::||.::||..|.:|.:|.||.::..||.||:|.....:.:.:.|.|.:.|||
  Fly   337 --------ILLTSSRLFYAGANNGQMPEILTMIQIQRFTPTPAVLAMALLSMLYLTVSDIFALIN 393

Human   527 YVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEPMVCGVGVI 591
            ||.|..:|..||.:|.|..|||.:|.|.|||:|.::.|:.||:...|:.|....:.|:..|.|::
  Fly   394 YVGFATWLSIGVAVLCLPWLRWAQPNLPRPIRVPMVFPIVYLIATIFVTVVPMYASPVETGYGIL 458

Human   592 IILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQDAPEE 639
            :||:.:|::.:.:.|::||....:...|:|.:.|::..|:..|..|.:
  Fly   459 MILSSIPVYLVFIAWKNKPIWFQKTMVSLTRFLQKMLMVLGKQTKPAQ 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC7A10	XP_011525421.1	2A0308	15..635	CDD:273332	202/621 (33%)
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	200/603 (33%)