Protein Alignment SLC7A10 and gb

DIOPT Version :10

• Sequence 1: XP_011525421.1
• Gene: SLC7A10 / 56301
• HGNCID: 11058
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_651536.1
• Gene: gb / 43265
• FlyBaseID: FBgn0039487
• Length: 517
• Species: Drosophila melanogaster
• Alignment Length: 662
• Identity: 215/662 - (32%)
• Similarity: 326/662 - (49%)
• Gaps: 169/662 - (25%)

Human     2 AGHTQQPSGR--------GNP-----RPAPSPSPV----PGTVPGASERVALKKEIGLLSACTII 49
            |...|.||..        |||     :||.:|:..    .|:....|.||.:||::|||....||
  Fly     4 ADELQSPSSEMVLLTPSSGNPPSSIAQPAANPAEKAQCREGSAESDSSRVVIKKQLGLLEGVAII 68

Human    50 IGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIF 114
            :|.|.|||||:|||||:....|||.:|.:|||.|.::.:|:|||||||.|||||||||||:.|.:
  Fly    69 LGIIFGSGIFVSPKGVIREVESVGASLVIWVLCGLLSMIGALCYAELGTAIPKSGGDYAYIFEAY 133

Human   115 GGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPN-CIPPTTASRVLSMACLMLLTWVNSS 178
            |.|..||.||.|::|..||:.|::.:||::|||:|.|.. |..|..|.::|:...:..||::||.
  Fly   134 GSLPAFLYLWDAMMIFVPTTNAIMGLTFASYVLEPFFGGACEIPKIALQLLAAITICFLTYLNSY 198

Human   179 SVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEEL-RPSNAFAFWMTPS-VGHLALAFLQG 241
            .::..|::|::....|:.||.|||.|||:.:..|:.|.. ||     |..|.: .|.:::||..|
  Fly   199 YMKVTTKMQNVIMFTKIAALVLIILVGLVWMMMGNVENFTRP-----FDNTETDPGKMSVAFYSG 258

Human   242 SFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVVS 306
            .|:::|||:||::|||:.|..:||||||:||:||||.:|...|:||...:||.|:::|||:||..
  Fly   259 IFSYAGWNYLNFMTEELRDPYRNLPRAIYISLPLVTGIYVLANVAYLAVLSPSEMIASNAIAVTF 323

Human   307 G-PLLGPWLLPRPLPRPYTWPLYCAHPDLRGEAAGLLFLGHACLRGSVNLRRDQWLPVHLLQVTA 370
            | .:||.:.|..||                                             ::.::|
  Fly   324 GDKILGVFSLIIPL---------------------------------------------MVAISA 343

Human   371 LGRRGHGEGRLGCRCAPVMPWARGRDTCRGRGLPEAGMMIPHGNKCLITTGRQRKQEAGRLDEGE 435
            .|                                        |....|.|
  Fly   344 FG----------------------------------------GLSVHIMT--------------- 353

Human   436 NCPVGLLGPEQEVRGDSLRGTSGPKLRPRMWPVPISVPNARLCFSGAREGHLPSLLAMIHVRHCT 500
                                                  ::|:||.|||.||:|::|:.|.|:..|
  Fly   354 --------------------------------------SSRICFVGARNGHMPAILSHISVKSYT 380

Human   501 PIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPV 565
            |:|:|:..|..:.|:::|.|.|.||.|.|.:......:::..:|..|:.||.:.|||||.:.||.
  Fly   381 PLPSLVFLCFLSIVMLVVSDVYVLITYASIVESFFIMLSVSAVLYFRYTRPCMERPIKVAMWIPA 445

Human   566 AYLVFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFV 630
            .:::..|||:|......|...|:||:|.:.|:|.:::||.|::|||.|....:|:|...|:|.
  Fly   446 LFVIVCAFLVVVPIYVAPYEVGMGVLITIIGIPFYYVGVVWKNKPKWVQSTIDSVTFTCQKLF-- 508

Human   631 VYPQDAPEEEEN 642
               ..|.||:|:
  Fly   509 ---MSAKEEKED 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC7A10	XP_011525421.1	2A0308	15..635	CDD:273332	204/627 (33%)
gb	NP_651536.1	2A0308	32..515	CDD:273332	205/630 (33%)