Protein Alignment SLC7A10 and CG5535

DIOPT Version :10

• Sequence 1: XP_011525421.1
• Gene: SLC7A10 / 56301
• HGNCID: 11058
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_649019.2
• Gene: CG5535 / 39990
• FlyBaseID: FBgn0036764
• Length: 630
• Species: Drosophila melanogaster
• Alignment Length: 651
• Identity: 117/651 - (17%)
• Similarity: 216/651 - (33%)
• Gaps: 241/651 - (37%)

Human    31 SERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSV-----GLALFVWVLGGGVTAL-G 89
            |....|.|.:.......:.||:.:|.|:::.       :|.|     |.|:.|..|...:.:: .
  Fly    31 SNESKLAKVLSAFDLTALGIGSTLGVGVYVL-------AGEVSKQYAGPAVVVSFLIAAIASIFA 88

Human    90 SLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNC 154
            .|||||.|..:||:|..|.|.....|....||:.|:.:| .|....|.:....|.|:.|    .|
  Fly    89 GLCYAEFGARVPKAGSAYIYSYVTIGEFIAFLIGWNLIL-EYAIGSASVVKGLSTYLDQ----LC 148

Human   155 IPPTTA----------------SRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIG 203
            ..|.::                ..:.:....:|.:...:...:.:||:.::||       .|.:|
  Fly   149 GNPMSSFLGTHMPLNIEGMGAYPDLFAFVVTILFSLAIAVGAKESTRVNNVFT-------MLNLG 206

Human   204 VGLLQIFQGHFEELRPSNAFAFWMTPS------------VGHLALAFLQGS----FAFSGWNFLN 252
            |.|..|..|.| ::..||    |..|.            :.:.....::|:    :.|.|::.:.
  Fly   207 VVLFVIIAGLF-KVSSSN----WSIPKSQVPEGYGDGGFMPYGVSGIIKGAAVCFYGFIGFDCIA 266

Human   253 YVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVVSGPLLGPWLLPR 317
            ...||..:.:|::|.|:.:|:.::.       :|||            .|:.|...:|
  Fly   267 TAGEEAKNPKKSIPFAVIVSLAMIF-------LAYF------------GVSTVLTMML------- 305

Human   318 PLPRPYTWPLYCAHPDLRGEAAGLLFLGHACLRGSVNLRRDQWLPV-HLLQVTALGRRGHGEGRL 381
                ||                               ..:|:..|: |:.::..
  Fly   306 ----PY-------------------------------FEQDEKAPLPHVFRING----------- 324

Human   382 GCRCAPVMPWARGRDTCRGRGLPEAGMMIPHGNKCLITTGRQRKQEAGRLDEGENCPVGLLGPEQ 446
                     |                    |..:.:::.|..               .||.
  Fly   325 ---------W--------------------HVAEYVVSIGAM---------------FGLC---- 341

Human   447 EVRGDSLRGTSGPKLRPRMWPVPISVPNARLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGA 511
                .|:.|.        |:|:|      |:.|:.:.:|.|...|..|..::.||....::....
  Fly   342 ----SSMMGA--------MFPLP------RIVFAMSNDGLLFKFLGDISEKYKTPFKGTMITGML 388

Human   512 TAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWR---------------------RP-ALH 554
            |.::..|.:...|:|.:|....|.|.:....:|:||:.                     || ||.
  Fly   389 TGILAAVFNLSQLVNMMSIGTLLAYSMVASCVLMLRYEVDDRRESRIVANGRATGLEQDRPCALW 453

Human   555 RPI-----------KVNLLIPVAYLVFWAFLLVFSFI---SEPMVCGV----GVIIILTGVPIFF 601
            |.|           :.:.::..:..:|..:.:|||.|   .|..:..|    |:.::|..:|:..
  Fly   454 RRIFNLNGQTVPTKQTSRIVTYSVTLFSLWCMVFSQILTKFEEDLANVTSFDGIKLVLGTIPLAV 518

Human   602 L 602
            |
  Fly   519 L 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC7A10	XP_011525421.1	2A0308	15..635	CDD:273332	117/651 (18%)
CG5535	NP_649019.2	2A0303	20..585	CDD:273330	117/651 (18%)