Protein Alignment SLC7A10 and mnd

DIOPT Version :10

• Sequence 1: XP_011525421.1
• Gene: SLC7A10 / 56301
• HGNCID: 11058
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Alignment Length: 628
• Identity: 217/628 - (34%)
• Similarity: 322/628 - (51%)
• Gaps: 165/628 - (26%)

Human    18 PSPSPVPGTVPGASE--RVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWV 80
            |...|...|....|:  .|.|||:||||....||:|.|:|||||:||||||:.|||:|.:|.|||
  Fly    19 PPAEPNNSTADSGSQGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQSLIVWV 83

Human    81 LGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNY 145
            |.|.::.:|:|||||||..||||||||||:...||.|..||.||.|:||:.||..|:.::||:.|
  Fly    84 LSGVLSMVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITALTFAIY 148

Human   146 VLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIF 210
            :|:|.:|:|..|..|.::|:.|.:.:||.:|..:|:|.||:.|:|||.|::||.:|:|.|:..:|
  Fly   149 LLKPFWPSCDAPIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLF 213

Human   211 QGHFEELRPSNAFAFWMTP------SVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAI 269
            .|:.|.         |..|      ..|::||||..|.|::||||:||:||||:.|..:|||:||
  Fly   214 DGNTEH---------WDNPFSGGLQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAI 269

Human   270 FISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVVSG-PLLG--PWLLPRPLPRPYTWPLYCAH 331
            .||:|:||.:|..||||||:.:||.|:|||:||||..| .:||  .|::|        :.:.|:
  Fly   270 CISMPVVTVIYMITNIAYFSVLSPDEILSSDAVAVTFGDKMLGYMSWIMP--------FAVACS- 325

Human   332 PDLRGEAAGLLFLGHACLRGSVNLRRDQWLPVHLLQVTALGRRGHGEGRLGCRCAPVMPWARGRD 396
              ..|...|.:|
  Fly   326 --TFGSLNGAIF----------------------------------------------------- 335

Human   397 TCRGRGLPEAGMMIPHGNKCLITTGRQRKQEAGRLDEGENCPVGLLGPEQEVRGDSLRGTSGPKL 461
                                                                             
  Fly   336 ----------------------------------------------------------------- 335

Human   462 RPRMWPVPISVPNARLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLIN 526
                       .::||.|.|||.||||:.:::|:|...||:|:|:.....|.:::.:.|.|.|||
  Fly   336 -----------ASSRLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLIN 389

Human   527 YVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEPMVCGVGVI 591
            |||::..|...:::.|||.:|:::|...|||||||.:|:.||:...||::||....|.|.|:|.|
  Fly   390 YVSYVEALFTLISVSGLLWMRYKQPKTERPIKVNLALPIIYLIVCLFLVIFSCTQTPYVVGIGTI 454

Human   592 IILTGVPIFFLGVFWRSKP-KCVHRLTESMTHWGQELCFVVYP 633
            |||:|:|:::|.:   .|| |.:...::::..|..:. |:..|
  Fly   455 IILSGIPVYYLTI---HKPVKWLADTSQAINLWCSKF-FICMP 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC7A10	XP_011525421.1	2A0308	15..635	CDD:273332	217/628 (35%)
mnd	NP_524074.1	2A0308	22..496	CDD:273332	216/625 (35%)