Protein Alignment SLC7A10 and JhI-21

DIOPT Version :10

• Sequence 1: XP_011525421.1
• Gene: SLC7A10 / 56301
• HGNCID: 11058
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_609542.1
• Gene: JhI-21 / 34624
• FlyBaseID: FBgn0028425
• Length: 500
• Species: Drosophila melanogaster
• Alignment Length: 632
• Identity: 208/632 - (32%)
• Similarity: 311/632 - (49%)
• Gaps: 160/632 - (25%)

Human    12 GNPRPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLAL 76
            |||.||           ...|::.||:::.|::...||:|.||||||||:|.||..::.|||.:|
  Fly    24 GNPNPA-----------DGEEKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSL 77

Human    77 FVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMT 141
            .:|:..|.::.:|:|||||||..|.:|||||||:...||.|.|||.||.|:||:.||:..:::::
  Fly    78 LIWLTCGILSTIGALCYAELGTCITRSGGDYAYLLVSFGPLVGFLRLWIALLIIRPTTQTIVALS 142

Human   142 FSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGL 206
            |::|.::|.||.|.||..|.::|:..||.|||.:|..||:.:.::||:||.||||||.:||..||
  Fly   143 FAHYAVKPFFPECDPPQNAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGL 207

Human   207 LQIFQGHFEELRPSNAF-AFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIF 270
            ..:..|..|..|  |.: ..:...::|:   ||..|.|||.|||:||:||||:.|..|||||||:
  Fly   208 YYMATGELENFR--NPWEGIYTARNIGY---AFYSGLFAFGGWNYLNFVTEELQDPYKNLPRAIW 267

Human   271 ISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVVSG-PLLGPWLLPRPLPRPYTWPLYCAHPDL 334
            |::||||.:|...|:|||..::..|:|||.||||..| .:.||
  Fly   268 IAMPLVTSIYVLVNLAYFAVVNKPEMLSSLAVAVTFGNRVFGP---------------------- 310

Human   335 RGEAAGLLFLGHACLRGSVNLRRDQWLPVHLLQVTALGRRGHGEGRLGCRCAPVMPWARGRDTCR 399
                  |.|:                :|:.:
  Fly   311 ------LAFM----------------VPIFV---------------------------------- 319

Human   400 GRGLPEAGMMIPHGNKCLITTGRQRKQEAGRLDEGENCPVGLLGPEQEVRGDSLRGTSGPKLRPR 464
                            .|.|.|                                 |.:|
  Fly   320 ----------------ALSTFG---------------------------------GVNG------ 329

Human   465 MWPVPISVPNARLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVS 529
                 :...:|||..:||:|||||....:.||:..||||:|:..|..:.:::|..:.|.||||.|
  Fly   330 -----VLFTSARLFATGAQEGHLPKFFQLFHVKQQTPIPSLIFTCLMSLLMLLTDNVYQLINYFS 389

Human   530 FINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEPMVCGVGVIIIL 594
            .:.:|....:|.|:|.||.:||.|.|||||:|.:|:.::|....|::...:.||....:|:.|.|
  Fly   390 SVLWLSVVASIAGMLWLRHKRPDLPRPIKVHLALPITFMVSCVTLVLLPNLEEPQNLLIGIGITL 454

Human   595 TGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQDAPEEEE 641
            .|:|.::..:..:.||||..||:.|:.    |:|..::.....|..|
  Fly   455 AGIPFYYAFIARKKKPKCYGRLSNSVV----EICRAIFNTTIIESNE 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC7A10	XP_011525421.1	2A0308	15..635	CDD:273332	203/621 (33%)
JhI-21	NP_609542.1	2A0308	27..494	CDD:273332	203/624 (33%)