Protein Alignment SLC7A10 and sbm

DIOPT Version :10

• Sequence 1: XP_011525421.1
• Gene: SLC7A10 / 56301
• HGNCID: 11058
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_727785.1
• Gene: sbm / 32397
• FlyBaseID: FBgn0030574
• Length: 541
• Species: Drosophila melanogaster
• Alignment Length: 617
• Identity: 181/617 - (29%)
• Similarity: 282/617 - (45%)
• Gaps: 160/617 - (25%)

Human     9 SGRGNPRPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVG 73
            ||.|..|     .|:.......:..|.|::.:||.|...:|:|.:||||||:||.|:|..:||||
  Fly    58 SGTGRMR-----KPLERNGSTQNHVVHLERRLGLFSGVALIVGTMIGSGIFVSPSGLLVRTGSVG 117

Human    74 LALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVI 138
            ::..:|:..|.::.||:|.|||||.....||.::||..:.:|....||..|.:.|::.|:.:|:|
  Fly   118 VSFIIWLACGVLSLLGALAYAELGTMNTSSGAEWAYFMDAYGPAPAFLFSWVSTLVLKPSQMAII 182

Human   139 SMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIG 203
            .::|:.|.::.....|.||....:::::..::::.:||..||.....:|::||..||:|:.::|.
  Fly   183 CLSFAQYAVEAFVTECDPPRGVVKMVALVAIVMILFVNCYSVNLGMAVQNVFTAAKLVAVVVVIC 247

Human   204 VGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRA 268
            .|..::.||:.:.|  ||||...| |:||.:|.||..|.:|:.|||.|||||||:.:..|||||:
  Fly   248 GGAWKLMQGNTQHL--SNAFNGPM-PNVGAIATAFYTGLWAYDGWNNLNYVTEEIKNPSKNLPRS 309

Human   269 IFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVVSG-PLLG--PWLLPRPLPRPYTWPLYCA 330
            |.|.|||||..|...||:|..||||||::.|.||||..| .:||  .||:|
  Fly   310 IIIGIPLVTLCYALINISYLAAMSPQEMIESEAVAVTFGNRILGALAWLMP-------------- 360

Human   331 HPDLRGEAAGLLFLGHACLRGSVNLRRDQWLPVHLLQVTALGRRGHGEGRLGCRCAPVMPWARGR 395
                                               |.|| :...|...|.|         :|.|
  Fly   361 -----------------------------------LSVT-ISTFGSANGTL---------FAAG- 379

Human   396 DTCRGRGLPEAGMMIPHGNKCLITTGRQRKQEAGRLDEGENCPVGLLGPEQEVRGDSLRGTSGPK 460
                                                                             
  Fly   380 ----------------------------------------------------------------- 379

Human   461 LRPRMWPVPISVPNARLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLI 525
                           ||||:.:|||||..:|:.:|||..||.|.|:......:.::|.|...:||
  Fly   380 ---------------RLCFAASREGHLLDILSYVHVRRLTPAPGLIFHSLIASAMVLHGTIDSLI 429

Human   526 NYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEPMVCGV-G 589
            ::.||..::.||..:|.|:::|:.:|...||.||.::|||..||...:|:.......|.|..: .
  Fly   430 DFFSFTAWIFYGGAMLALIVMRYTKPNYPRPYKVPIIIPVVVLVISVYLVAAPIFETPRVEYLYA 494

Human   590 VIIILTG----VPIFFLGVFWRSKPKCVHRLT 617
            ::.|..|    ||...||:    .|:.::::|
  Fly   495 LLFIFAGLIFYVPFVKLGM----TPRFMNKVT 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC7A10	XP_011525421.1	2A0308	15..635	CDD:273332	178/611 (29%)
sbm	NP_727785.1	2A0308	53..532	CDD:273332	181/617 (29%)