Protein Alignment PRPH and LamC

DIOPT Version :9

• Sequence 1: XP_005269082.1
• Gene: PRPH / 5630
• HGNCID: 9461
• Length: 471
• Species: Homo sapiens
• Sequence 2: NP_001260974.1
• Gene: LamC / 36615
• FlyBaseID: FBgn0010397
• Length: 640
• Species: Drosophila melanogaster
• Alignment Length: 486
• Identity: 133/486 - (27%)
• Similarity: 231/486 - (47%)
• Gaps: 93/486 - (19%)

Human    38 SRFSSSRLLGSASPSSSVRLGSFRSPRAGAGALLRLPSERLDFSMAEALNQEFLATRSNEKQELQ 102
            ||.|:|..:|.||.||.|...|..||..                          .:|..||:|||
  Fly    13 SRASTSTPVGGASTSSRVGATSPTSPTR--------------------------TSRQQEKEELQ 51

Human   103 ELNDRFANFIEKVRFLEQQNAALRGELSQAR---GQEPARADQLCQQELRELRRELELLGRERDR 164
            .||||.|.:|:::|.||.:|:.|..||:.|:   .:|.:....:.::||...|:.|:...:|:.:
  Fly    52 HLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAK 116

Human   165 VQVERDGLAEDLAALKQRLEEETRKREDAEHNLVLF----------------------------- 200
            ::::...|.|:...||.||:::|::...||:|..|:
  Fly   117 LEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLADRKKFEDQAKELA 181

Human   201 -------------RKDVDDATLSRLELERKIESLMDEIEFLKKLHEEELRDLQVSVESQQVQQVE 252
                         ||.::..||:|::||.:.:||.:|:.|..::|.:||.:.:   ..:|::..|
  Fly   182 LENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETR---SRRQIEISE 243

Human   253 VEATV----KPELTAALRDIRAQYESIAAKNLQEAEEWYKSKYADLSDAANRNHEALRQAKQEMN 313
            ::..:    :.:|..:|:::|.|||.....|.:|.|..|.::..:|..||||..:....|.:|:.
  Fly   244 IDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALATEEVR 308

Human   314 ESRRQIQSLTCEVDGLRGTNEALLRQLRELEEQFALEAGGYQAGAARLEEELRQLKEEMARHLRE 378
            ..|.:|..|..::..|..||..|..::||||.....|...:....|.||.||:::::|||..|:|
  Fly   309 LMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAHQLQE 373

Human   379 YQELLNVKMALDIEIATYRKLLEGEESRISV--PVHSFASLNIKTTVPEVEPPQDSHSRKTVLIK 441
            ||.|:::|::||:|||.|.|||.|||.|:::  |........|.:....:.....|.|.:.
  Fly   374 YQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTASASSRSGRV---- 434

Human   442 TIETRNGEQVVT------ESQKEQRSELDKS 466
               |.:|.:..|      .:.|.:|:.:|:|
  Fly   435 ---TPSGRRSATPGISGSSAVKRRRTVIDES 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRPH	XP_005269082.1	Filament_head	13..95	CDD:282575	13/56 (23%)
		Filament	96..406	CDD:278467	107/358 (30%)
		BAR	<199..373	CDD:299863	52/219 (24%)
LamC	NP_001260974.1	Filament	45..401	CDD:278467	107/358 (30%)
		ATP-synt_B	<67..>142	CDD:304375	20/74 (27%)
		MreC	<178..>224	CDD:302802	11/45 (24%)
		LTD	473..574	CDD:279300

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910