DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stx16 and Syx7

DIOPT Version :9

Sequence 1:	XP_021332963.1	Gene:	stx16 / 562857	ZFINID:	ZDB-GENE-060810-113	Length:	324	Species:	Danio rerio
Sequence 2:	NP_730632.1	Gene:	Syx7 / 36173	FlyBaseID:	FBgn0267849	Length:	282	Species:	Drosophila melanogaster

Alignment Length:	270	Identity:	68/270 - (25%)
Similarity:	123/270 - (45%)	Gaps:	42/270 - (15%)

- Green bases have known domain annotations that are detailed below.

Zfish    81 GVDEIQYE-----ITRIRQKMKELASLHDKHMNR-PTLDDSSEEEHAIEITTQEITQMFHRCQRA 139
            |:.||.::     |....||:::..|...:.:|: .|..||.|       ..:::.|:.....:.
  Fly    17 GLSEIDFQRLAQIIATSIQKVQQNVSTMQRMVNQLNTPQDSPE-------LKKQLHQIMTYTNQL 74

Zfish   140 VTGLQTQ--------SYHCTEQENRLLTNVVSSLA--QSLQELSLNFRHTQSGYLKRMKN----- 189
            ||....|        ..|...|.:||:....::|.  ||:|..:.:...|.   |::.:.
  Fly    75 VTDTNNQINEVDKCKERHLKIQRDRLVDEFTAALTAFQSVQRKTADIEKTA---LRQARGDSYNI 136

Zfish   190 -REERSKHFFDSGPLVEEDEDIALYDRGFTDDQLVLVQQNTVM--------VEEREREIRQIVQS 245
             |...|.....|.....:.::.:.::..|.:.:....|..|.|        :||:|:.||::..:
  Fly   137 ARPPGSSRTGSSNSSASQQDNNSFFEDNFFNRKSNQQQMQTQMEEQADLQALEEQEQVIRELENN 201

Zfish   246 ISDLNEIFRDLAGMVVEQGTVLDRIDFNVEQSCVKTEEGLQQLQKAEQYQKKNRKMLVIL--ILF 308
            |..:|||::.|..:|.|||..:|.|:..|||:.:...:|.:.|:||..|:.|.||..:||  ||.
  Fly   202 IVGVNEIYKKLGALVYEQGLTVDSIESQVEQTSIFVSQGTENLRKASSYRNKVRKKKLILVGILS 266

Zfish   309 VIVVVLILIL 318
            .:::.:||||
  Fly   267 AVLLAIILIL 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stx16	XP_021332963.1	SynN	73..300	CDD:330835	58/248 (23%)
stx16	XP_021332963.1	SNARE_syntaxin16	232..290	CDD:277198	21/57 (37%)
Syx7	NP_730632.1	Syntaxin_2	30..126	CDD:291208	22/105 (21%)
		COG5325	<97..276	CDD:227635	48/181 (27%)
		SNARE	188..247	CDD:304603	21/58 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3589
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940