DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PROP1 and hbn

DIOPT Version :9

Sequence 1:	NP_006252.4	Gene:	PROP1 / 5626	HGNCID:	9455	Length:	226	Species:	Homo sapiens
Sequence 2:	NP_788420.1	Gene:	hbn / 47894	FlyBaseID:	FBgn0008636	Length:	409	Species:	Drosophila melanogaster

Alignment Length:	152	Identity:	66/152 - (43%)
Similarity:	75/152 - (49%)	Gaps:	32/152 - (21%)

- Green bases have known domain annotations that are detailed below.

Human    65 RPHSRRRHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQER 129
            ||...||.||||:..||.|||.||.:.||||::.||.||....|||||:||||||||||.||:|:
  Fly   149 RPRKVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWFQNRRAKWRKREK 213

Human   130 SLLQPLAHLSPAAFSSFLPESTACPYSYAAPPPPVTCFPHPYSHALPSQPSTGGAFALSHQSEDW 194
            .:.|..|       ...|||.....:....|.||         |.||..|.       |.|||.|
  Fly   214 FMNQDKA-------GYLLPEQGLPEFPLGIPLPP---------HGLPGHPG-------SMQSEFW 255

Human   195 YP--TLH-------PAPAGHLP 207
            .|  .||       .|.||.||
  Fly   256 PPHFALHQHFNPAAAAAAGLLP 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PROP1	NP_006252.4	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..75		5/9 (56%)
		Homeobox	72..126	CDD:395001	34/53 (64%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	196..226		8/21 (38%)
hbn	NP_788420.1	Homeobox	156..209	CDD:278475	34/52 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910