DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment MEPCE and CG1239

DIOPT Version :10

Sequence 1:NP_062552.2 Gene:MEPCE / 56257 HGNCID:20247 Length:689 Species:Homo sapiens
Sequence 2:NP_649577.1 Gene:CG1239 / 40706 FlyBaseID:FBgn0037368 Length:300 Species:Drosophila melanogaster


Alignment Length:326 Identity:118/326 - (36%)
Similarity:174/326 - (53%) Gaps:66/326 - (20%)


- Green bases have known domain annotations that are detailed below.


Human   363 RKRRRTSSKSEAGARGGGQGSKEKGRGSWGGRHHHHHPLPAAGFKKQQRKFQYGNYCKYYGYR-- 425
            ::.::..|..||.:|...|..|::       .|.:..|:     :.:...|:||||..|||.|  
  Fly    37 KRLKKEESNVEATSRPPAQSPKKR-------LHLNGKPM-----QNKDLNFKYGNYKHYYGKRIL 89

Human   426 NPSCEDGRLRVL--KPEWFRGRDVLDLGCNVGHLTLSIACKWGPSRMVGLDIDSRLIHSARQNIR 488
            |....|.||.||  :|:.||.:.:||:|||.|||::.||.|:....:||||||..||:.|::.:.
  Fly    90 NKDFHDIRLDVLGTQPDLFRNKQLLDIGCNSGHLSIQIARKFEVKSLVGLDIDRGLINDAQKTVS 154

Human   489 HYLSEELRLPPQTLEGDPGAEGEEGTTTVRKRSCFPASLTASRGPIAAPQVPLDGADTSVFPNNV 553
            |.                            ||...|..           .:|           ::
  Fly   155 HL----------------------------KRHATPGQ-----------GIP-----------HI 169

Human   554 VFVTGNYVLDRDDLVEAQTPEYDVVLCLSLTKWVHLNWGDEGLKRMFRRIYRHLRPGGILVLEPQ 618
            .||.|||||:.|.|:|.:.|::||:||||:|||:|||:.|.|||:.|||:|..|||||.|:||||
  Fly   170 QFVHGNYVLEDDVLLEIERPQFDVILCLSVTKWIHLNFCDSGLKQAFRRMYLQLRPGGKLILEPQ 234

Human   619 PWSSYGKRKTLTETIYKNYYRIQLKPEQFSSYLTSPDVGFSSYELVATPHNTSKGFQRPVYLFHK 683
            .:..|.:||.|:|.|..||..|:.:|:.|:.||.||:|||:..:|:..|.:...||:||:.:|.|
  Fly   235 SFDGYKRRKKLSEQIRDNYNAIKFRPDHFTEYLLSPEVGFAEMKLMGIPEHCKVGFKRPIQIFTK 299

Human   684 A 684
            :
  Fly   300 S 300

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MEPCENP_062552.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..167
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 258..314
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 332..407 8/43 (19%)
Tam 443..616 CDD:443282 63/172 (37%)
Bin3 575..683 CDD:462022 55/107 (51%)
CG1239NP_649577.1 UbiG 90..232 CDD:441829 71/191 (37%)
Bin3 191..299 CDD:462022 55/107 (51%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.