Protein Alignment PRODH and Prodh

DIOPT Version :10

• Sequence 1: NP_057419.5
• Gene: PRODH / 5625
• HGNCID: 9453
• Length: 600
• Species: Homo sapiens
• Sequence 2: NP_001129250.3
• Gene: Prodh / 680409
• RGDID: 1590932
• Length: 599
• Species: Rattus norvegicus
• Alignment Length: 600
• Identity: 488/600 - (81%)
• Similarity: 534/600 - (89%)
• Gaps: 1/600 - (0%)

Human     1 MALRRALPALRPCIPRFVPLSTAPASREQPAAGPAAVPGGGSATAVRPPVPAVDFGNAQEAYRSR 65
            |||:|.. .||...||...|||.|.::|||.|.|.|:.|.|:|.|||||||||||.|.|||||||
  Rat     1 MALKRVF-LLRSVAPRVAALSTKPRAQEQPPANPEALRGCGAAEAVRPPVPAVDFTNTQEAYRSR 64

Human    66 RTWELARSLLVLRLCAWPALLARHEQLLYVSRKLLGQRLFNKLMKMTFYGHFVAGEDQESIQPLL 130
            |:|||||:||||||||.|.|||.||||..|:|||||||:|.:|||||||||||||||||||:||:
  Rat    65 RSWELARNLLVLRLCASPVLLAHHEQLFQVARKLLGQRMFERLMKMTFYGHFVAGEDQESIRPLI 129

Human   131 RHYRAFGVSAILDYGVEEDLSPEEAEHKEMESCTSAAERDGSGTNKRDKQYQAHWAFGDRRNGVI 195
            ||.:||||..||||||||||||||||.||||||||.|||||||.|||:||||.|.||||||:|||
  Rat   130 RHNKAFGVGFILDYGVEEDLSPEEAERKEMESCTSEAERDGSGANKREKQYQVHPAFGDRRDGVI 194

Human   196 SARTYFYANEAKCDSHMETFLRCIEASGRVSDDGFIAIKLTALGRPQFLLQFSEVLAKWRCFFHQ 260
            ||||||||:|||||::||..|:||||||..||.||.|||||||||||||||||:||.:||.||||
  Rat   195 SARTYFYASEAKCDNYMENLLQCIEASGGASDGGFSAIKLTALGRPQFLLQFSDVLTRWRQFFHQ 259

Human   261 MAVEQGQAGLAAMDTKLEVAVLQESVAKLGIASRAEIEDWFTAETLGVSGTMDLLDWSSLIDSRT 325
            ||.||||||..|:||||||||||||:||:||:||||||.|||.||||||||:|||||:|||||||
  Rat   260 MAAEQGQAGRPAVDTKLEVAVLQESIAKMGISSRAEIERWFTPETLGVSGTVDLLDWNSLIDSRT 324

Human   326 KLSKHLVVPNAQTGQLEPLLSRFTEEEELQMTRMLQRMDVLAKKATEMGVRLMVDAEQTYFQPAI 390
            :||:||||||.|||||||||||||||||.||.|||||||||||.|.|.|||||:||||:||||||
  Rat   325 QLSRHLVVPNVQTGQLEPLLSRFTEEEEQQMKRMLQRMDVLAKVAREAGVRLMIDAEQSYFQPAI 389

Human   391 SRLTLEMQRKFNVEKPLIFNTYQCYLKDAYDNVTLDVELARREGWCFGAKLVRGAYLAQERARAA 455
            |||||||||:|||:||.||||:||||||||||||:|:||:||||||||||||||||:|||||||.
  Rat   390 SRLTLEMQRRFNVDKPFIFNTFQCYLKDAYDNVTIDMELSRREGWCFGAKLVRGAYMAQERARAV 454

Human   456 EIGYEDPINPTYEATNAMYHRCLDYVLEELKHNAKAKVMVASHNEDTVRFALRRMEELGLHPADH 520
            |||||||||||||||||||||||:||||||||:.||:|||||||||||.|.|.||:||||||||.
  Rat   455 EIGYEDPINPTYEATNAMYHRCLNYVLEELKHSTKAEVMVASHNEDTVSFTLCRMKELGLHPADG 519

Human   521 RVYFGQLLGMCDQISFPLGQAGYPVYKYVPYGPVMEVLPYLSRRALENSSLMKGTHRERQLLWLE 585
            :|.|||||||||||||||||||:|||||||||||||||||||||||||||:|||..|||||||.|
  Rat   520 QVCFGQLLGMCDQISFPLGQAGFPVYKYVPYGPVMEVLPYLSRRALENSSIMKGAQRERQLLWQE 584

Human   586 LLRRLRTGNLFHRPA 600
            |.||||||:|||.||
  Rat   585 LCRRLRTGSLFHHPA 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRODH	NP_057419.5	PLN02681	31..578	CDD:215366	453/546 (83%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..177		18/21 (86%)
Prodh	NP_001129250.3	PLN02681	47..594	CDD:215366	459/546 (84%)