Protein Alignment PRODH and prodhb

DIOPT Version :10

• Sequence 1: NP_057419.5
• Gene: PRODH / 5625
• HGNCID: 9453
• Length: 600
• Species: Homo sapiens
• Sequence 2: XP_073808074.1
• Gene: prodhb / 100537991
• ZFINID: ZDB-GENE-101116-1
• Length: 603
• Species: Danio rerio
• Alignment Length: 548
• Identity: 359/548 - (65%)
• Similarity: 442/548 - (80%)
• Gaps: 2/548 - (0%)

Human    52 AVDFGNAQEAYRSRRTWELARSLLVLRLCAWPALLARHEQLLYVSRKLLGQRLFNKLMKMTFYGH 116
            ::||...:|||:|:.|.||.|||:|.:||::..|:.::::::.:|||||||::|.:.|||||||.
Zfish    56 SIDFELTREAYKSKDTLELLRSLVVFKLCSYDILVDKNKEIIDLSRKLLGQKMFEQFMKMTFYGQ 120

Human   117 FVAGEDQESIQPLLRHYRAFGVSAILDYGVEEDLSPEEAEHKEMESCTSAAERDGSGTNKRDKQY 181
            ||||||.:||:|:::..:|:||.|:|||.||||||.||||.||||||.|.:|::..|.:.|:|::
Zfish   121 FVAGEDHQSIRPVVQKNQAYGVGAVLDYSVEEDLSQEEAERKEMESCMSTSEKESPGVDHREKKF 185

Human   182 QAHWAFGDRRNGVISARTYFYANEAKCDSHMETFLRCIEASGRVSDDGFIAIKLTALGRPQFLLQ 246
            .||..|||||.||.||||||||:|||||.||||||.||:|||..|:|||.|||:|||||||||||
Zfish   186 TAHRRFGDRREGVTSARTYFYADEAKCDQHMETFLNCIKASGGSSEDGFSAIKMTALGRPQFLLQ 250

Human   247 FSEVLAKWRCFFHQMAVEQGQAGLAAMDTKLEVAVLQESVAKLGIASRAEIEDWFTAETLGVSGT 311
            |||||.|||.||..:|.:||:.|:..::.||::..||..:|:||  :...|:.:|:...|..||.
Zfish   251 FSEVLVKWRRFFSFLASKQGKDGMEVLEQKLDLEQLQMCLARLG--AEGNIQSFFSDGRLHSSGI 313

Human   312 MDLLDWSSLIDSRTKLSKHLVVPNAQTGQLEPLLSRFTEEEELQMTRMLQRMDVLAKKATEMGVR 376
            :|:|||:.|||.|.|:|..|||||.|||||||||||||||||.||.|||||:|||||.|.|.|||
Zfish   314 VDMLDWNRLIDERMKISDLLVVPNLQTGQLEPLLSRFTEEEERQMKRMLQRLDVLAKHAVENGVR 378

Human   377 LMVDAEQTYFQPAISRLTLEMQRKFNVEKPLIFNTYQCYLKDAYDNVTLDVELARREGWCFGAKL 441
            ||||||||||||||||||:||:|.||.:|.::|||||||||:|:|||::||||:|||||||.|||
Zfish   379 LMVDAEQTYFQPAISRLTVEMKRSFNRDKAVVFNTYQCYLKEAFDNVSMDVELSRREGWCFAAKL 443

Human   442 VRGAYLAQERARAAEIGYEDPINPTYEATNAMYHRCLDYVLEELKHNAKAKVMVASHNEDTVRFA 506
            |||||:.|||:|||||||||||||.||:||.||||||||||||::.|.|..|||||||.|||:..
Zfish   444 VRGAYMYQERSRAAEIGYEDPINPDYESTNRMYHRCLDYVLEEIQRNKKVNVMVASHNLDTVKHT 508

Human   507 LRRMEELGLHPADHRVYFGQLLGMCDQISFPLGQAGYPVYKYVPYGPVMEVLPYLSRRALENSSL 571
            ||||.|:||.|.|.:|.|||||||||||||||.|||:|||||||||||.||:|||||||.||...
Zfish   509 LRRMNEMGLQPTDKKVCFGQLLGMCDQISFPLAQAGFPVYKYVPYGPVNEVIPYLSRRAQENRGF 573

Human   572 MKGTHRERQLLWLELLRRLRTGNLFHRP 599
            |||...||:|||.||:|||.:|.:.:.|
Zfish   574 MKGVQMERELLWKELMRRLSSGQILYTP 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRODH	NP_057419.5	PLN02681	31..578	CDD:215366	347/525 (66%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..177		11/21 (52%)
prodhb	XP_073808074.1	None