| Sequence 1: | NP_066385.2 | Gene: | ZNF253 / 56242 | HGNCID: | 13497 | Length: | 499 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001030308.1 | Gene: | Zfp748 / 212276 | MGIID: | 1916455 | Length: | 888 | Species: | Mus musculus |
| Alignment Length: | 664 | Identity: | 261/664 - (39%) |
|---|---|---|---|
| Similarity: | 331/664 - (49%) | Gaps: | 187/664 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Human 4 LQFRDVAIEFSLEEWHCLDTAQRNLYRDVMLENYRNLVFLGIVVSKPDLVTCLEQGKKPLTMERH 68
Human 69 EMIAKPPVMSSHFAQDLWPENIQNSFQIGMLR--------RYEEC------------RHDNLQLK 113
Human 114 KGCK--------------------SVGE--HKVHK-GGYNGLNQCLTT-----TQKEIFQCDKYG 150
Human 151 KVFHKFSNSNTYKTRHTGINLF------------------------------------------- 172
Human 173 ----------------------------------------KCIICGKAFKRSSTLTTHKKIHTGE 197
Human 198 KPYRCEECGKAFNQSANLTTHKRIHTGEKPYRCEECGKAFKQSSNLTTHKKIHTGEKPYKCEECG 262
Human 263 KAFNRSTDLTTHKIVHTGEKPYKCEECGKAFKHPSHVTTHKKIHTRGKPYNCEECGKSFKHCSNL 327
Human 328 TIHKRIHTGEKPYKCEECGKAFHLSSHLTTHKILHTGEKPYRCRECGKAFNHSTTLFSHEKI--- 389
Human 390 -------------------------HTGEKPYKCDECGKTFTWPSIL------------------ 411
Human 412 ----------SKHKRTHTGEKPYKCEECGKSFTASSTLTTHKRIHTGEKPYKCEECGKAFNWSSD 466
Human 467 LNKHKKIHIERKPY 480 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ZNF253 | NP_066385.2 | KRAB | 4..62 | CDD:214630 | 40/57 (70%) |
| KRAB | 6..43 | CDD:279668 | 27/36 (75%) | ||
| C2H2 Zn finger | 146..166 | CDD:275368 | 5/19 (26%) | ||
| COG5048 | 170..>497 | CDD:227381 | 193/450 (43%) | ||
| C2H2 Zn finger | 174..194 | CDD:275368 | 9/19 (47%) | ||
| zf-H2C2_2 | 187..211 | CDD:290200 | 16/23 (70%) | ||
| C2H2 Zn finger | 202..222 | CDD:275368 | 11/19 (58%) | ||
| zf-H2C2_2 | 214..239 | CDD:290200 | 14/24 (58%) | ||
| C2H2 Zn finger | 230..250 | CDD:275368 | 8/19 (42%) | ||
| zf-H2C2_2 | 242..267 | CDD:290200 | 18/24 (75%) | ||
| C2H2 Zn finger | 258..278 | CDD:275368 | 12/19 (63%) | ||
| zf-H2C2_2 | 270..295 | CDD:290200 | 19/24 (79%) | ||
| C2H2 Zn finger | 286..306 | CDD:275368 | 10/19 (53%) | ||
| C2H2 Zn finger | 314..334 | CDD:275368 | 9/19 (47%) | ||
| zf-H2C2_2 | 326..350 | CDD:290200 | 17/23 (74%) | ||
| C2H2 Zn finger | 342..362 | CDD:275368 | 12/19 (63%) | ||
| zf-H2C2_2 | 354..379 | CDD:290200 | 16/24 (67%) | ||
| C2H2 Zn finger | 370..390 | CDD:275368 | 9/47 (19%) | ||
| zf-H2C2_2 | 383..406 | CDD:290200 | 17/50 (34%) | ||
| C2H2 Zn finger | 398..418 | CDD:275368 | 14/47 (30%) | ||
| zf-H2C2_2 | 411..434 | CDD:290200 | 17/50 (34%) | ||
| C2H2 Zn finger | 426..446 | CDD:275368 | 12/19 (63%) | ||
| zf-H2C2_2 | 439..462 | CDD:290200 | 17/22 (77%) | ||
| C2H2 Zn finger | 454..474 | CDD:275368 | 10/19 (53%) | ||
| Zfp748 | NP_001030308.1 | KRAB | 5..63 | CDD:214630 | 40/57 (70%) |
| KRAB | 5..44 | CDD:279668 | 28/38 (74%) | ||
| C2H2 Zn finger | 83..103 | CDD:275368 | 3/19 (16%) | ||
| C2H2 Zn finger | 139..159 | CDD:275368 | 0/19 (0%) | ||
| C2H2 Zn finger | 167..187 | CDD:275368 | 3/19 (16%) | ||
| C2H2 Zn finger | 195..215 | CDD:275368 | 5/19 (26%) | ||
| C2H2 Zn finger | 279..298 | CDD:275368 | 0/18 (0%) | ||
| C2H2 Zn finger | 306..326 | CDD:275368 | 9/19 (47%) | ||
| C2H2 Zn finger | 334..354 | CDD:275368 | 11/19 (58%) | ||
| zf-H2C2_2 | 346..371 | CDD:290200 | 14/24 (58%) | ||
| C2H2 Zn finger | 362..382 | CDD:275368 | 8/19 (42%) | ||
| zf-H2C2_2 | 375..399 | CDD:290200 | 18/23 (78%) | ||
| C2H2 Zn finger | 390..410 | CDD:275368 | 12/19 (63%) | ||
| C2H2 Zn finger | 418..438 | CDD:275368 | 10/19 (53%) | ||
| COG5048 | 442..875 | CDD:227381 | 110/227 (48%) | ||
| C2H2 Zn finger | 446..466 | CDD:275368 | 9/19 (47%) | ||
| zf-H2C2_2 | 461..483 | CDD:290200 | 18/21 (86%) | ||
| C2H2 Zn finger | 474..494 | CDD:275368 | 12/19 (63%) | ||
| C2H2 Zn finger | 502..522 | CDD:275368 | 8/19 (42%) | ||
| C2H2 Zn finger | 530..550 | CDD:275368 | 0/19 (0%) | ||
| C2H2 Zn finger | 558..578 | CDD:275368 | 11/19 (58%) | ||
| C2H2 Zn finger | 586..606 | CDD:275368 | 3/19 (16%) | ||
| zf-H2C2_2 | 601..623 | CDD:290200 | 16/21 (76%) | ||
| C2H2 Zn finger | 614..634 | CDD:275368 | 12/19 (63%) | ||
| C2H2 Zn finger | 642..662 | CDD:275368 | 10/19 (53%) | ||
| C2H2 Zn finger | 670..690 | CDD:275368 | |||
| zf-H2C2_2 | 683..707 | CDD:290200 | |||
| C2H2 Zn finger | 698..718 | CDD:275368 | |||
| C2H2 Zn finger | 726..746 | CDD:275368 | |||
| C2H2 Zn finger | 754..774 | CDD:275368 | |||
| C2H2 Zn finger | 782..802 | CDD:275368 | |||
| zf-H2C2_2 | 797..819 | CDD:290200 | |||
| C2H2 Zn finger | 810..830 | CDD:275368 | |||
| C2H2 Zn finger | 838..858 | CDD:275368 | |||
| C2H2 Zn finger | 866..886 | CDD:275368 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 75 | 1.000 | Domainoid score | I51179 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| HGNC | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| NCBI | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100020 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.810 | |||||